Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924971 | 0.94 | CCR3 (0.40) | CCR3ALDH1A1LMNAHCAR1 | |
| SCHEMBL2930809 | 0.90 | LMNA (0.40) | KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL1760878 | 0.89 | FAAH (0.47) | CCR3KDRLMNA | |
| SCHEMBL2927088 | 0.88 | GPR6 (0.41) | KMT2AMEN1GPR6 | |
| SCHEMBL2931482 | 0.88 | MEN1 (0.39) | KMT2AMEN1HCAR1GPR6 | |
| SCHEMBL3049811 | 0.88 | MEN1 (0.42) | KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL2930508 | 0.88 | GPR6 (0.34) | HCAR1GPR6 | |
| SCHEMBL2929411 | 0.87 | ADORA2A (0.41) | KMT2AALDH1A1MEN1 | |
| SCHEMBL2930504 | 0.85 | FAAH (0.45) | KMT2AALDH1A1LMNAMEN1GPR6 | |
| SCHEMBL2931169 | 0.85 | OGA (0.38) | KMT2ALMNAMEN1GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027132-B1 | THIAZOLO-PYRAMIDINE / PYRIDINE UREA DERIVATIVES AS ADENOSINE A2B RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-09-15 | — | — | EP | claimed |