Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277259 | 0.83 | BBOX1 (0.39) | ALDH1A1GMNNLMNATP53TSHR | |
| SCHEMBL1119820 | 0.78 | APP (0.38) | ALDH1A1LMNATSHRSMN1; SMN2GAA | |
| SCHEMBL15561485 | 0.78 | NPSR1 (0.33) | ALDH1A1LMNATP53GAAPAOX | |
| Sulfuric Acid SCHEMBL29789453 | 0.74 | PAOX (0.39) | ALDH1A1LMNATSHRSMN1; SMN2GAA | |
| SCHEMBL11140857 | 0.73 | APP (0.38) | ALDH1A1LMNATSHRSMN1; SMN2GAA | |
| SCHEMBL1948513 | 0.72 | KDM1A (0.43) | ALDH1A1TSHRSMN1; SMN2GAACA12 | |
| SCHEMBL3023756 | 0.72 | PAOX (0.50) | ALDH1A1GAAPAOXKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL3009329 | 0.70 | KDM1A (0.46) | ALDH1A1TSHRSMN1; SMN2GAACA12 | |
| Hydrochloric Acid SCHEMBL3024738 | 0.70 | SMOX (0.52) | ALDH1A1PMP22GAAPAOXKDM4E | |
| SCHEMBL17291817 | 0.70 | PAOX (0.48) | ALDH1A1GAAPAOXKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290295-A | Hydrophobic monomer and preparation method thereof, weak gel and preparation method and application thereof, and drilling fluid | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290295-A | Hydrophobic monomer and preparation method thereof, weak gel and preparation method and application thereof, and drilling fluid | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118206471-A | Hydrophobic crosslinking monomer, thickener for fracturing fluid, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115701421-B | Crosslinking monomer and polymer microsphere plugging material and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-12-08 | — | — | CN | disclosed |