SCHEMBL9277259

SCHEMBL9277259

C=CCNCCS(=O)(=O)[O-].[Na+]

nearest known ligand 0.39

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 known ✓ O43570 1/20 0.32
CA1 known ✓ P00915 1/20 0.32
CA2 known ✓ P00918 1/20 0.32
BBOX1 O75936 1/20 0.39
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
GMNN O75496 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
THPO P40225 1/20 0.33
HBB P68871 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL29273698 0.83 ALDH1A1 (0.35) BBOX1KDM4EGMNNALDH1A1LMNA
SCHEMBL9786717 0.81 BBOX1 (0.38) BBOX1KDM4EMAPTALOX15GMNN
SCHEMBL29518815 0.78 BBOX1 (0.50) BBOX1KDM4EMAPTALOX15GMNN
SCHEMBL2255511 0.76 NPSR1 (0.31)
SCHEMBL466387 0.76 LMNA (0.33) KDM4EMAPTALDH1A1LMNATSHR
SCHEMBL1527793 0.76 CA2 (0.37) CA12CA1CA2CA9
SCHEMBL9277263 0.74 PTGS1 (0.32) KDM4EMAPTALDH1A1LMNATSHR
SCHEMBL28577494 0.74 PTGS1 (0.32) KDM4EMAPTALDH1A1LMNATSHR
SCHEMBL30859705 0.73 BBOX1 (0.41) BBOX1KDM4EMAPTALOX15GMNN
SCHEMBL9659291 0.71 BBOX1 (0.33) BBOX1KDM4EMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7278097-A None JP disclosed
JP-4360863-A None JP disclosed
US-5464502-A Anionic sulfonate surfactants in the washing and pulping operation BETZ PAPERCHEM, INC. (US) 1995-11-07 US disclosed
JP-H07278097-A METHOD FOR PRODUCING SODIUM N-ALKYLAMINOETHANESULFONATE TOSOH CORP 1995-10-24 JP disclosed
JP-H04360863-A PRODUCTION OF SODIUM N-ALKYLAMINOETHANESULFONATE TOSOH CORP 1992-12-14 JP disclosed