SCHEMBL2929573

SCHEMBL2929573

Fc1cc(F)c(I)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.36
CES1 P23141 3/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ERN1 O75460 1/20 0.33
RAPGEF4 Q8WZA2 1/20 0.32
TGM2 P21980 1/20 0.31
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28854043 0.97 CES2 (0.35) CES2CES1CA12CA1CA9
SCHEMBL14733078 0.84 CES2 (0.32) CES2CES1CA12CA1CA9
SCHEMBL29920955 0.80 MAPT (0.37) CES2CES1ALDH1A1MAPTKMT2A
SCHEMBL4745988 0.80 CA9 (0.44) CES2CES1CA12CA1CA9
SCHEMBL29812175 0.80 CA9 (0.44) CES2CES1CA12CA1CA9
SCHEMBL18775342 0.80 CES2 (0.30) CES2CES1
SCHEMBL12074048 0.80 RAPGEF4 (0.40) CES2CES1RAPGEF4
SCHEMBL4607963 0.80 MAPT (0.37) CES2CES1ALDH1A1MAPTKMT2A
SCHEMBL18101290 0.79 TTR (0.33)
SCHEMBL21279638 0.76 CES2 (0.32) CES2CES1ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1362860-B1 Method for producing tetrakis (fluoraryl)borate magnesium compound NIPPON CATALYTIC CHEM IND (JP) 2010-09-15 EP claimed
US-7205441-B2 Method for producing tetrakis (fluoroaryl) borate-magnesium compound NIPPON SHOKUBAI CO., LTD. (JP) 2007-04-17 US claimed
US-20030216598-A1 Method for producing tetrakis ( fluoroaryl) borate-magnesium compound NIPPON SHOKUBAI CO., LTD. (JP) 2003-11-20 US claimed
EP-1362860-A1 Method for producing tetrakis (fluoroaryl) borate magnesium compound Nippon Shokubai Co., Ltd. (JP) 2003-11-19 EP claimed
US-20250074938-A1 CELL-PERMEANT INHIBITORS OF VIRAL CYSTEINE PROTEASES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2025-03-06 US disclosed
CN-119462647-A Aromatic condensed ring compound, pharmaceutical composition containing aromatic condensed ring compound and application of aromatic condensed ring compound 杭州禹泓医药科技有限公司 2025-02-18 CN disclosed
CN-118693282-B Secondary battery and preparation method and application thereof 蜂巢能源科技股份有限公司 2024-12-03 CN disclosed
CN-118693282-A Secondary battery and preparation method and application thereof 蜂巢能源科技股份有限公司 2024-09-24 CN disclosed
CN-118451090-A Amide antiviral compound 海南先声药业有限公司 2024-08-06 CN disclosed
EP-3681928-B1 PROCESS OF MANUFACTURING POLYOLS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-01 EP disclosed
US-20230371357-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-16 US disclosed
US-20230309379-A1 LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-28 US disclosed
CN-1356331-A Process for preparing metallic fluoroaryl ampound NIPPON CATALYTIC CHEM IND (JP) 2002-07-03 CN disclosed
EP-1211255-A2 Method for producing fluoroaryl metal compound Nippon Shokubai Co., Ltd. (JP) 2002-06-05 EP disclosed
US-20020065426-A1 Method for producing fluoroaryl metal compound NIPPON SHOKUBAI CO., LTD (JP) 2002-05-30 US disclosed
US-6235222-B1 REACTING, IN SOLVENT CONTAINING CHAIN ETHER SOLVENT, HYDROCARBON MAGNESIUM HALIDE WITH FLUOROARYL HALIDE NIPPON SHOKUBAI CO., LTD. (JP) 2001-05-22 US disclosed
EP-0995753-A2 Method for manufacturing fluoroaryl magnesium halide Nippon Shokubai Co., Ltd. (JP) 2000-04-26 EP disclosed
EP-0109606-B1 PROCESS FOR THE FORMYLATION OF ARYL HALIDES BAYER AG (DE) 1986-01-22 EP disclosed
US-4536344-A USING A PHOSPINE OR PHOSPHITE BAYER AKTIENGESELLSCHAFT (DE) 1985-08-20 US disclosed
EP-0109606-A1 Process for the formylation of aryl halides BAYER AG (DE) 1984-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074938-A1 CELL-PERMEANT INHIBITORS OF VIRAL CYSTEINE PROTEASES ACE, TMPRSS2, ACE2 CES2 293/4885CES1 127/4885CA12 606/4885
US-20030216598-A1 Method for producing tetrakis ( fluoroaryl) borate-magnesium compound KRAS, MGAM, CA3 CES2 3957/4885CES1 4605/4885CA12 747/4885
US-20230371357-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE L1CAM, CHRM1, FOXM1 CES2 2295/4885CES1 1770/4885CA12 2600/4885
US-20020065426-A1 Method for producing fluoroaryl metal compound DDT, TERT, HACL2 CES2 3276/4885CES1 3890/4885CA12 3603/4885
US-20230309379-A1 LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE ORGANOMETALLIC COMPOUND CRY1, LEF1, LAGE3 CES2 2364/4885CES1 1181/4885CA12 3438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.