Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314118 | 0.91 | POLQ (0.33) | POLQ | |
| SCHEMBL29314114 | 0.88 | POLQ (0.32) | POLQ | |
| SCHEMBL29314123 | 0.81 | ALDH1A1 (0.34) | POLQ | |
| SCHEMBL29314122 | 0.74 | CRHR1 (0.34) | POLQ | |
| SCHEMBL29314119 | 0.72 | CRHR1 (0.36) | POLQ | |
| SCHEMBL29314125 | 0.70 | SMN1; SMN2 (0.40) | POLQ | |
| SCHEMBL29314124 | 0.67 | SMN1; SMN2 (0.40) | POLQ | |
| SCHEMBL29313855 | 0.67 | POLQ (0.37) | POLQ | |
| SCHEMBL29314308 | 0.65 | GAA (0.32) | POLQ | |
| SCHEMBL29313854 | 0.65 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |