Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLQ | O75417 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314119 | 0.91 | CRHR1 (0.36) | POLQGAANPSR1MEN1KMT2A | |
| SCHEMBL29314114 | 0.82 | POLQ (0.32) | ALDH1A1POLQGAAMEN1KMT2A | |
| SCHEMBL29314122 | 0.82 | CRHR1 (0.34) | ALDH1A1POLQGAANPSR1MEN1 | |
| SCHEMBL29314117 | 0.81 | POLQ (0.31) | POLQ | |
| SCHEMBL29313853 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL29314305 | 0.76 | POLQ (0.30) | POLQ | |
| SCHEMBL29314165 | 0.72 | GAA (0.33) | ALDH1A1POLQGAANPSR1 | |
| SCHEMBL29314118 | 0.72 | POLQ (0.33) | POLQGAA | |
| SCHEMBL29314124 | 0.70 | SMN1; SMN2 (0.40) | ALDH1A1POLQGAANPSR1MEN1 | |
| SCHEMBL29313854 | 0.69 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |