Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLQ | O75417 | 4/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314183 | 0.85 | GAA (0.30) | GAANPSR1 | |
| SCHEMBL29314127 | 0.83 | POLQ (0.41) | GAANPSR1POLQKDM4EALDH1A1 | |
| SCHEMBL29314130 | 0.81 | RORC (0.34) | GAANPSR1POLQMCOLN3KDM4E | |
| SCHEMBL29314170 | 0.73 | GAA (0.31) | GAANPSR1POLQMCOLN3 | |
| SCHEMBL29314119 | 0.72 | CRHR1 (0.36) | GAANPSR1POLQ | |
| SCHEMBL29314123 | 0.72 | ALDH1A1 (0.34) | GAANPSR1POLQALDH1A1 | |
| SCHEMBL29314172 | 0.69 | POLQ (0.36) | GAANPSR1POLQKDM4EALDH1A1 | |
| SCHEMBL29314181 | 0.68 | GAA (0.33) | GAANPSR1POLQMCOLN3 | |
| SCHEMBL29314122 | 0.63 | CRHR1 (0.34) | GAANPSR1POLQMCOLN3KDM4E | |
| SCHEMBL7225307 | 0.55 | CES2 (0.60) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |