Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 11/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 11/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314121 | 0.70 | POLQ (0.44) | ROCK2ROCK1 | |
| SCHEMBL29315913 | 0.66 | ROCK1 (0.39) | ROCK2ROCK1 | |
| SCHEMBL29315909 | 0.66 | ROCK2 (0.46) | ROCK2ROCK1 | |
| SCHEMBL29316278 | 0.64 | NPBWR1 (0.39) | ROCK2ROCK1 | |
| SCHEMBL29316276 | 0.58 | ROCK2 (0.39) | ROCK2ROCK1 | |
| SCHEMBL31009157 | 0.57 | POLQ (0.46) | ROCK2ROCK1 | |
| SCHEMBL13036088 | 0.56 | LRRK2 (0.50) | ROCK2ROCK1 | |
| SCHEMBL25795129 | 0.55 | NOTUM (0.46) | ROCK1 | |
| SCHEMBL20040983 | 0.55 | NPBWR1 (0.44) | ROCK2ROCK1 | |
| SCHEMBL28199128 | 0.55 | ROCK2 (0.44) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |