Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314846 | 0.91 | TLR7 (0.41) | ADORA2BTLR7TLR8NOS3NOS1 | |
| SCHEMBL29314743 | 0.87 | TLR8 (0.39) | ADORA2BTLR7TLR8NOS3NOS1 | |
| SCHEMBL29314853 | 0.84 | NOS3 (0.35) | TLR7TLR8NOS3NOS1 | |
| SCHEMBL23037652 | 0.84 | TLR8 (0.45) | TLR7TLR8ADORA3ADORA2AADORA1 | |
| SCHEMBL29314847 | 0.83 | ADORA2A (0.36) | TLR7TLR8ADORA3ADORA2AADORA1 | |
| SCHEMBL23037673 | 0.83 | TLR8 (0.40) | TLR7TLR8ADORA3ADORA2AADORA1 | |
| SCHEMBL30539884 | 0.83 | TLR8 (0.40) | TLR7TLR8ADORA3ADORA2AADORA1 | |
| SCHEMBL29314851 | 0.82 | ADORA3 (0.36) | TLR7TLR8NOS3NOS1NOS2 | |
| SCHEMBL29314611 | 0.82 | HPGD (0.36) | TLR7TLR8 | |
| SCHEMBL29314861 | 0.81 | NOS1 (0.36) | ADORA2BTLR7TLR8NOS1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | NLRP3, NLRP1, PYCARD | ADORA2B 1785/4885TLR7 236/4885TLR8 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.