Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26786746 | 0.93 | NOS3 (0.35) | NOS3NOS1 | |
| SCHEMBL29314607 | 0.84 | ADORA2B (0.42) | NOS3NOS1TLR8TLR7 | |
| SCHEMBL29314847 | 0.81 | ADORA2A (0.36) | TLR8TLR7 | |
| SCHEMBL29314861 | 0.81 | NOS1 (0.36) | NOS1TLR8TLR7 | |
| SCHEMBL23037577 | 0.80 | TLR8 (0.43) | NOS3NOS1TLR8TLR7 | |
| SCHEMBL29314717 | 0.80 | ADORA3 (0.35) | TLR8TLR7 | |
| SCHEMBL26786698 | 0.79 | ADORA2B (0.33) | — | |
| SCHEMBL29315565 | 0.79 | TLR7 (0.38) | TLR8TLR7 | |
| SCHEMBL23037627 | 0.79 | TLR8 (0.47) | TLR8TLR7 | |
| SCHEMBL29314864 | 0.78 | TLR8 (0.38) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | NLRP3, NLRP1, PYCARD | NOS3 501/4885NOS1 309/4885TLR8 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.