SCHEMBL29323211

SCHEMBL29323211

CCOC(=O)Cc1coc2c(NC(=O)CN3CCN(C(=O)OC(C)(C)C)CC3)cccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43
KDM4E B2RXH2 5/20 0.43
HSD17B10 Q99714 3/20 0.43
LMNA P02545 3/20 0.43
POLB P06746 3/20 0.43
MAPK1 P28482 2/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ITGA4 P13612 1/20 0.43
ITGB7 P26010 1/20 0.43
TSHR P16473 1/20 0.42
MAPT P10636 3/20 0.42
CETP P11597 1/20 0.40
TP53 P04637 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324151 0.82 L3MBTL1 (0.41) KDM4EPOLBL3MBTL1TP53
SCHEMBL29323213 0.75 DDB1 (0.49) ALDH1A1CHRM2CHRM4CHRM1CHRM3
SCHEMBL29324051 0.75 CHRM2 (0.46) ALDH1A1CHRM2CHRM4CHRM1CHRM3
SCHEMBL29324050 0.74 CHRM2 (0.47) ALDH1A1CHRM2CHRM4CHRM1CHRM3
SCHEMBL31254090 0.71 ITGA4 (0.48) ALDH1A1CHRM2CHRM4CHRM1CHRM3
SCHEMBL18072532 0.71 CHRM3 (0.53) ALDH1A1CHRM2CHRM4CHRM1CHRM3
SCHEMBL15192026 0.71 CHRM2 (0.46) ALDH1A1CHRM2CHRM4CHRM1CHRM3
SCHEMBL15191988 0.70 CHRM2 (0.47) ALDH1A1CHRM2CHRM4CHRM1CHRM3
SCHEMBL29324049 0.70 CHRM2 (0.47) ALDH1A1CHRM2CHRM4CHRM1CHRM3
SCHEMBL31661208 0.69 MAPT (0.49) ALDH1A1CHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed