SCHEMBL29324151

SCHEMBL29324151

CCOC(=O)Cc1coc2c(NC(=O)C(F)(F)C3CCN(C(=O)OC(C)(C)C)CC3)cccc12

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
GPR119 Q8TDV5 5/20 0.38
RAB9A P51151 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TP53 P04637 2/20 0.37
TGFBR1 P36897 2/20 0.37
KDM4E B2RXH2 2/20 0.37
PKM P14618 1/20 0.37
POLB P06746 2/20 0.36
CCR8 P51685 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324249 0.85 TP53 (0.38) L3MBTL1GPR119RAB9AMEN1KMT2A
SCHEMBL29323211 0.82 ALDH1A1 (0.44) L3MBTL1TP53KDM4EPOLB
SCHEMBL29324152 0.77 DDB1 (0.49) GPR119TGFBR1KDM4EPKMCCR8
SCHEMBL29324248 0.76 SMN1; SMN2 (0.41) GPR119TGFBR1KDM4EPKMCCR8
SCHEMBL29324244 0.76 TGFBR1 (0.41) GPR119RAB9ATGFBR1KDM4EPKM
SCHEMBL29324241 0.71 TGFBR1 (0.43) GPR119MEN1KMT2ATGFBR1KDM4E
SCHEMBL29324252 0.69 DDB1 (0.47) GPR119
SCHEMBL14635943 0.68 L3MBTL1 (0.51) L3MBTL1GPR119MEN1KMT2ATP53
SCHEMBL30659463 0.67 HPGD (0.46) L3MBTL1GPR119MEN1KMT2AKDM4E
SCHEMBL29324846 0.67 KDM4E (0.49) L3MBTL1GPR119RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed