SCHEMBL29323813

SCHEMBL29323813

C=Cc1ccc(C(=O)OC(CS(=O)(=O)c2ccccc2)CS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.39
MCL1 Q07820 2/20 0.39
HSD11B1 P28845 8/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP1A2 P05177 1/20 0.38
GAA P10253 1/20 0.38
CYP2C19 P33261 1/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323852 0.88 CA2 (0.41) TDP1CA12CA9
SCHEMBL29323853 0.87 TDP1 (0.39) POLBHSD11B1TDP1CA9
SCHEMBL29323843 0.84 HSD11B1 (0.43) HSD11B1TDP1CYP2C19CA12CA9
SCHEMBL29323835 0.78 TAS1R3 (0.40) TDP1CA12CA9PDCD1CD274
SCHEMBL29323826 0.77 HSD11B1 (0.41) RAB9AHSD11B1TDP1CYP1A2GAA
SCHEMBL29323769 0.77 TDP1 (0.44) POLBRAB9AMCL1HSD11B1TDP1
SCHEMBL20792094 0.77 ALDH1A1 (0.51) RAB9AHSD11B1TDP1CYP1A2GAA
SCHEMBL29324634 0.72 PSIP1 (0.47) POLBHSD11B1TDP1CYP1A2GAA
SCHEMBL27928510 0.71 PDCD1 (0.45) POLBRAB9ACYP1A2TP53TSHR
SCHEMBL440529 0.70 F2 (0.48) POLBRAB9ATDP1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed