Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760650 | 0.82 | GAA (0.49) | CYP1A2HTTKDM4EMAPTKMT2A | |
| SCHEMBL13990739 | 0.82 | DHODH (0.43) | LMNACYP1A2KDM4EPKM | |
| SCHEMBL7757528 | 0.80 | POLB (0.58) | LMNAKDM4EKMT2ASMN1; SMN2PKM | |
| SCHEMBL803410 | 0.79 | CYP1A2 (0.60) | LMNAL3MBTL1CYP1A2HTTKDM4E | |
| SCHEMBL29324754 | 0.76 | CYP1A2 (0.39) | LMNAL3MBTL1CYP1A2GFER | |
| SCHEMBL3531515 | 0.76 | LMNA (0.66) | LMNAL3MBTL1CYP1A2HTTKDM4E | |
| SCHEMBL7761439 | 0.76 | KMT2A (0.52) | L3MBTL1HTTMAPTKMT2AMITF | |
| SCHEMBL23479555 | 0.74 | HTR1A (0.51) | LMNAL3MBTL1HTTKDM4EMAPT | |
| SCHEMBL438604 | 0.73 | NCF1 (0.63) | LMNAL3MBTL1CYP1A2KDM4EKMT2A | |
| SCHEMBL3760247 | 0.73 | LMNA (0.61) | LMNAL3MBTL1CYP1A2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, LPL, PNLIP | LMNA 1185/4885L3MBTL1 403/4885CYP1A2 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.