Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 3/20 | 0.34 |
| ▸ | LATS2 | Q9NRM7 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17453169 | 0.79 | CYP1A2 (0.57) | CYP1A2NCF1LMNADHODHACHE | |
| SCHEMBL803410 | 0.78 | CYP1A2 (0.60) | CYP1A2NCF1LMNAL3MBTL1SSTR4 | |
| SCHEMBL29324195 | 0.76 | LMNA (0.58) | CYP1A2LMNAL3MBTL1GFER | |
| SCHEMBL24175000 | 0.76 | NCF1 (0.59) | CYP1A2NCF1TERT | |
| SCHEMBL22956798 | 0.76 | CYP1A2 (0.40) | CYP1A2NCF1LMNADHODHACHE | |
| SCHEMBL21237376 | 0.75 | MAOA (0.40) | CYP1A2ACHEMAOAALOX5PTGS1 | |
| SCHEMBL10327439 | 0.74 | CCNC (0.40) | CYP1A2MAPK10ALOX5PTGS1PTGS2 | |
| SCHEMBL13437809 | 0.74 | TERT (0.54) | CYP1A2NCF1L3MBTL1GFERTERT | |
| SCHEMBL13990739 | 0.74 | DHODH (0.43) | CYP1A2LMNADHODH | |
| SCHEMBL7760650 | 0.74 | GAA (0.49) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, LPL, PNLIP | CYP1A2 424/4885NCF1 3938/4885LMNA 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.