SCHEMBL29324244

SCHEMBL29324244

CC(C)(C)OC(=O)N1CCC(C(F)(F)C(=O)Nc2cccc3c(O)cc(=O)oc23)CC1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 5/20 0.41
KDM4E B2RXH2 2/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
PTPN2 P17706 1/20 0.39
PTPN1 P18031 1/20 0.39
PTPN6 P29350 1/20 0.39
GPR119 Q8TDV5 3/20 0.39
PKM P14618 1/20 0.39
CCR8 P51685 1/20 0.38
STS P08842 2/20 0.38
BACE1 P56817 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324050 0.80 CHRM2 (0.47) KDM4EBACE1
SCHEMBL29324248 0.78 SMN1; SMN2 (0.41) TGFBR1KDM4ETHRBPTPN2PTPN1
SCHEMBL29324241 0.78 TGFBR1 (0.43) TGFBR1KDM4EMAPTPTPN2PTPN1
SCHEMBL29324152 0.76 DDB1 (0.49) TGFBR1KDM4EPTPN2PTPN1PTPN6
SCHEMBL29324151 0.76 L3MBTL1 (0.41) TGFBR1KDM4EGPR119PKMCCR8
SCHEMBL29324845 0.76 MAPK8 (0.45) KDM4EGPR119PKMRAB9A
SCHEMBL29324249 0.75 TP53 (0.38) TGFBR1KDM4EMAPTTHRBGPR119
SCHEMBL29324252 0.75 DDB1 (0.47) GPR119
SCHEMBL29324722 0.74 GPR119 (0.39) TGFBR1KDM4ETHRBGPR119PKM
SCHEMBL29324503 0.71 CHRM2 (0.42) KDM4EBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed