Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.37 |
| ▸ | GALR2 | O43603 | 4/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | GALR1 | P47211 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329528 | 0.91 | SYK (0.36) | SIRT2SIRT1SIRT3PRKCQGALR2 | |
| SCHEMBL29330430 | 0.86 | PRKCQ (0.43) | SIRT2SIRT1SIRT3PRKCQSYK | |
| SCHEMBL29329292 | 0.86 | SIRT2 (0.41) | SIRT2SIRT1SIRT3PRKCQSYK | |
| SCHEMBL29329869 | 0.85 | ESR1 (0.42) | SIRT2SIRT1SIRT3ESR1 | |
| SCHEMBL29330342 | 0.84 | SYK (0.40) | SIRT2SIRT1SIRT3PRKCQSYK | |
| SCHEMBL29330433 | 0.83 | SYK (0.41) | SIRT2SIRT1SIRT3PRKCQSYK | |
| SCHEMBL29330428 | 0.80 | ESR1 (0.42) | PRKCQGALR2SYKESR1 | |
| SCHEMBL29329290 | 0.80 | PRKCQ (0.42) | PRKCQSYKMETESR1 | |
| SCHEMBL29330563 | 0.79 | PRKCQ (0.39) | SIRT2SIRT1SIRT3PRKCQSYK | |
| SCHEMBL29329725 | 0.79 | PRKCQ (0.40) | PRKCQSYKMETESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |