Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 6/20 | 0.34 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329120 | 0.96 | PRKCQ (0.34) | PRKCQSYKSIRT2SIRT1SIRT3 | |
| SCHEMBL29330430 | 0.88 | PRKCQ (0.43) | PRKCQSYKSIRT2SIRT1SIRT3 | |
| SCHEMBL29330428 | 0.85 | ESR1 (0.42) | PRKCQSYKESR1KCNH2EGFR | |
| SCHEMBL29329528 | 0.85 | SYK (0.36) | PRKCQSYKSIRT2SIRT1SIRT3 | |
| SCHEMBL29330342 | 0.85 | SYK (0.40) | PRKCQSYKSIRT2SIRT1SIRT3 | |
| SCHEMBL29330433 | 0.84 | SYK (0.41) | PRKCQSYKSIRT2SIRT1SIRT3 | |
| SCHEMBL29329935 | 0.83 | SCN5A (0.39) | PRKCQSYKSCN5ASCN9AESR1 | |
| SCHEMBL29329004 | 0.82 | PRKCQ (0.38) | PRKCQSYKPRKCDESR1RET | |
| SCHEMBL29329292 | 0.81 | SIRT2 (0.41) | PRKCQSYKSIRT2SIRT1SIRT3 | |
| SCHEMBL29329117 | 0.81 | CDK2 (0.39) | PRKCQSYKPRKCDESR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |