Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694497 | 0.95 | PREP (0.45) | HPGDMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL17128208 | 0.86 | NR1H2 (0.48) | HPGDMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL20587386 | 0.79 | PREP (0.48) | HPGDMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL4264465 | 0.76 | HPGD (0.55) | HPGDMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL31209057 | 0.76 | HPGD (0.51) | HPGDMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL14196264 | 0.76 | HPGD (0.51) | HPGDMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL34473834 | 0.76 | HPGD (0.51) | HPGDMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL13085760 | 0.76 | HPGD (0.55) | HPGDMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL31064202 | 0.75 | HPGD (0.48) | HPGDMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL1094778 | 0.75 | HPGD (0.57) | HPGDMEN1ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399457-B2 | Pharmaceutical compounds | NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) | 2013-03-19 | — | — | US | disclosed |
| EP-2149575-B1 | Diazabicyclic compounds as opioid receptor agonists | NEUROSCIENZE PHARMANESS S C A R L (IT) | 2012-10-24 | — | — | EP | disclosed |
| US-20100029622-A1 | MICROEMULSIONS | NEUROSCIENZE PHARMANESS S.C.A.R.L. (IT) | 2010-02-04 | — | — | US | disclosed |
| US-20100029622-A1 | MICROEMULSIONS | NEUROSCIENZE PHARMANESS S.C.A.R.L. (IT) | 2010-02-04 | — | — | US | disclosed |
| US-20100028257-A1 | PHARMACEUTICAL COMPOUNDS | NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) | 2010-02-04 | — | — | US | disclosed |
| EP-2149575-A1 | Diazabicyclic compounds as opioid receptor agonists | Neuroscienze Pharmaness S.C. A R.L. (IT) | 2010-02-03 | — | — | EP | disclosed |
| EP-2149370-A1 | Diazabicyclic compounds and microemulsions thereof | Neuroscienze Pharmaness S.C. A R.L. (IT) | 2010-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100028257-A1 | PHARMACEUTICAL COMPOUNDS | OPRD1, OPRK1, OPRM1 | HPGD 1106/4885MEN1 3616/4885ALDH1A1 1449/4885 |
| US-20100029622-A1 | MICROEMULSIONS | LIPA, APOB, LIPC | HPGD 4710/4885MEN1 1138/4885ALDH1A1 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.