SCHEMBL29353318

SCHEMBL29353318

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(N)=O)C(C)C

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20816299 1.00 GLP1R (0.80) GLP1R
SCHEMBL29743095 0.98 GLP1R (0.81) GLP1R
SCHEMBL29362765 0.98 GLP1R (0.83) GLP1R
SCHEMBL29363146 0.98 GLP1R (0.83) GLP1R
SCHEMBL31731011 0.98 GLP1R (0.83) GLP1R
SCHEMBL30721588 0.98 GLP1R (0.83) GLP1R
SCHEMBL29359146 0.98 GLP1R (0.83) GLP1R
SCHEMBL29823404 0.98 GLP1R (0.83) GLP1R
SCHEMBL29942457 0.98 GLP1R (0.83) GLP1R
SCHEMBL27827907 0.98 GLP1R (0.83) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 690 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4691496-A1 PHARMACEUTICAL PREPARATION CONTAINING GLP-1 FUSION PROTEIN AND USE THEREOF Guangzhou Innogen Pharmaceutical Group Co., Ltd. (CN) 2026-02-11 — — EP claimed
US-12544371-B2 Methods and compositions for treating acute lung injury and acute respiratory distress syndrome CALCIMEDICA, INC. (US) 2026-02-10 — — US claimed
US-20250367218-A1 METHODS OF TREATING METABOLIC DISORDERS AND COMBINATION PRODUCTS FOR USE IN THE SAME BATTHYANY CARLOS (UY) 2025-12-04 — — US claimed
US-12435149-B2 Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (GIPR) in combination with GLP-1 agonists AMGEN INC. (US) 2025-10-07 — — US claimed
EP-3787631-B1 MODULATORS OF ORPHAN NUCLEAR RECEPTORS FOR NASH AND OTHER METABOLIC DISORDERS UNIV EMORY (US) 2025-09-10 — — EP claimed
CN-120037358-A Improved combination therapy of fusion proteins of GLP-1 receptor agonists 广州银诺医药集团股份有限公司 2025-05-27 — — CN claimed
CN-119909159-A Use of improved fusion proteins of GLP-1 receptor agonists in the treatment of diseases 广州银诺医药集团股份有限公司 2025-05-02 — — CN claimed
US-20250108121-A1 METHOD FOR PRODUCING AN ANTIBODY PEPTIDE CONJUGATE AMGEN INC. 2025-04-03 — — US claimed
US-12257282-B2 Mixtures and formulations CAMARUS AB (SE) 2025-03-25 — — US claimed
US-20240424057-A1 METHODS AND COMPOSITION OF INHIBITING ASPROSIN MEDIATED OREXIGENESIS AND/OR GLUCOGENSIS UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER 2024-12-26 — — US claimed
US-20220401523-A1 FGF21 COMPOUND / GLP-1R AGONIST COMBINATIONS WITH OPTIMIZED ACTIVITY RATIO SANOFI SA (FR) 2022-12-22 — — US claimed
WO-2022258805-A1 TREATMENT OF OBESITY AND OBESITY-RELATED DISORDERS ANTAG THERAPEUTICS APS (DK) 2022-12-15 — — WO claimed
US-11519034-B2 Non-invasive diagnostic of non-alcoholic fatty liver diseases, non-alcoholic steatohepatitis and/or liver fibrosis GENFIT (FR) 2022-12-06 — — US claimed
US-20220362187-A1 COMBINATION THERAPY COMPRISING COMPOUNDS OF FORMULA (I) AND GLP-1 RECEPTOR AGONISTS GENFIT (FR) 2022-11-17 — — US claimed
EP-4074327-A1 THERAPEUTIC AGENTS COMPRISING ELASTIN-LIKE PEPTIDES Duke University (US) 2022-10-19 — — EP claimed
US-20220315632-A1 COMBINATION OF DIETARY PEPTIDES DIET4LIFE APS (DK) 2022-10-06 — — US claimed
CN-109789214-B Mixtures and formulations comprising alkyl ammonium EDTA 卡姆拉斯公司 2022-06-28 — — CN claimed
EP-4000630-A1 ELEVATED INTRACRANIAL PRESSURE TREATMENT Invex Therapeutics Ltd (AU) 2022-05-25 — — EP claimed
EP-3236937-B1 CONTROLLED-RELEASE FORMULATIONS CAMURUS AB (SE) 2022-05-04 — — EP claimed
EP-3952855-A1 COMBINATION THERAPY COMPRISING COMPOUNDS OF FORMULA (I) AND GLP-1 RECEPTOR AGONISTS Genfit (FR) 2022-02-16 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544371-B2 Methods and compositions for treating acute lung injury and acute respiratory distress syndrome ORAI1, MAVS, CASR GLP1R 1013/4885
US-20250108121-A1 METHOD FOR PRODUCING AN ANTIBODY PEPTIDE CONJUGATE CTSD, DNPEP, CTSZ GLP1R 1455/4885
US-20250367218-A1 METHODS OF TREATING METABOLIC DISORDERS AND COMBINATION PRODUCTS FOR USE IN THE SAME GLP1R, GPR119, IAPP GLP1R 1/4885
US-12257282-B2 Mixtures and formulations PHOSPHO1, TTPA, LIPC GLP1R 3346/4885
US-20220362187-A1 COMBINATION THERAPY COMPRISING COMPOUNDS OF FORMULA (I) AND GLP-1 RECEPTOR AGONISTS GLP1R, GIPR, GPR119 GLP1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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