SCHEMBL29358407

SCHEMBL29358407

O=C(O)[C@H](Cc1ccc(O)c(O)c1)NN1C(=O)C=CC1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM6B O15054 1/20 0.51
▸ KDM4E B2RXH2 4/20 0.50
▸ ALOX15 P16050 4/20 0.50
▸ HIF1A Q16665 4/20 0.50
▸ HSD17B10 Q99714 4/20 0.50
▸ RECQL P46063 3/20 0.50
▸ TDP1 Q9NUW8 3/20 0.50
▸ LCK P06239 2/20 0.50
▸ USP2 O75604 2/20 0.50
▸ ADORA3 P0DMS8 2/20 0.50
▸ HTR2A P28223 2/20 0.50
▸ PTGS2 P35354 2/20 0.50
▸ EGFR P00533 1/20 0.50
▸ FYN P06241 1/20 0.50
▸ PTGS1 P23219 1/20 0.50
▸ SLC7A5 Q01650 1/20 0.50
▸ CA1 P00915 4/20 0.48
▸ CA2 P00918 4/20 0.48
▸ MME P08473 1/20 0.46
▸ ACE P12821 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29024434 0.81 MME (0.49) MMECYP1A2FOLH1
SCHEMBL30724831 0.79 KDM6B (0.64) KDM6BKDM4EALOX15HIF1AHSD17B10
SCHEMBL29669984 0.77 KDM6B (0.62) KDM6BKDM4EALOX15HIF1AHSD17B10
SCHEMBL5063603 0.77 KDM6B (0.62) KDM6BKDM4EALOX15HIF1AHSD17B10
SCHEMBL29429645 0.77 KDM6B (0.62) KDM6BKDM4EALOX15HIF1AHSD17B10
SCHEMBL30915529 0.76 KDM6B (0.60) KDM6BKDM4EALOX15HIF1AHSD17B10
SCHEMBL32662363 0.76 KDM6B (0.60) KDM6BKDM4EALOX15HIF1AHSD17B10
SCHEMBL31284349 0.76 KDM6B (0.65) KDM6BKDM4EALOX15HIF1AHSD17B10
SCHEMBL3736877 0.76 KDM6B (0.60) KDM6BKDM4EALOX15HIF1AHSD17B10
SCHEMBL22473033 0.76 CA2 (0.61) KDM6BKDM4EALOX15HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041764-A1 EXTRACELLULAR VESICLES FOR VACCINE DELIVERY LONZA SALES AG (CH) 2026-02-12 — — US disclosed
US-12502427-B2 Extracellular vesicles for vaccine delivery LONZA SALES AG (CH) 2025-12-23 — — US disclosed
EP-3068439-B1 OLIGOPEPTIDE AND METHODS FOR PRODUCING CONJUGATES THEREOF HOFFMANN LA ROCHE (CH) 2024-06-26 — — EP disclosed
US-11992527-B2 Extracellular vesicles for vaccine delivery LONZA SALES AG (CH) 2024-05-28 — — US disclosed
US-20240108747-A1 EXTRACELLULAR VESICLE CONJUGATES AND USES THEREOF LONZA SALES AG (CH) 2024-04-04 — — US disclosed
US-20230263885-A1 EXTRACELLULAR VESICLES FOR VACCINE DELIVERY CODIAK BIOSCIENCES, INC. (US) 2023-08-24 — — US disclosed
CN-109897089-B Integrin ligand VS polypeptide and application thereof in preparation of tumor targeting diagnosis and treatment drug delivery system 复旦大学 2023-08-22 — — CN disclosed
US-20220168415-A1 EXTRACELLULAR VESICLES FOR VACCINE DELIVERY CODIAK BIOSCIENCES, INC. (US) 2022-06-02 — — US disclosed
EP-3941937-A2 EXTRACELLULAR VESICLES FOR VACCINE DELIVERY Codiak BioSciences, Inc. (US) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041764-A1 EXTRACELLULAR VESICLES FOR VACCINE DELIVERY EXOSC10, EXOSC5, HLA-DRB1 KDM6B 2294/4885KDM4E 1894/4885ALOX15 3331/4885
US-12502427-B2 Extracellular vesicles for vaccine delivery HAVCR2, CD74, HMGB1 KDM6B 1966/4885KDM4E 2469/4885ALOX15 2166/4885
US-11992527-B2 Extracellular vesicles for vaccine delivery HAVCR2, CD74, HMGB1 KDM6B 1966/4885KDM4E 2469/4885ALOX15 2166/4885
US-20240108747-A1 EXTRACELLULAR VESICLE CONJUGATES AND USES THEREOF EXOSC5, EXOSC10, EXOSC4 KDM6B 851/4885KDM4E 1452/4885ALOX15 3485/4885
US-20230263885-A1 EXTRACELLULAR VESICLES FOR VACCINE DELIVERY HAVCR2, CD74, HMGB1 KDM6B 1966/4885KDM4E 2469/4885ALOX15 2166/4885
US-20220168415-A1 EXTRACELLULAR VESICLES FOR VACCINE DELIVERY HAVCR2, CD74, HMGB1 KDM6B 1966/4885KDM4E 2469/4885ALOX15 2166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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