SCHEMBL29359346

SCHEMBL29359346

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CC(C)C)C(=O)NCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ERAP2 Q6P179 4/20 0.57
▸ EDNRA P25101 1/20 0.56
▸ MAGI3 Q5TCQ9 1/20 0.54
▸ IL1RN P18510 3/20 0.52
▸ MMP1 P03956 3/20 0.52
▸ ERAP1 Q9NZ08 2/20 0.52
▸ ECE1 P42892 4/20 0.51
▸ CASP1 P29466 1/20 0.51
▸ CASP3 P42574 1/20 0.51
▸ CASP4 P49662 1/20 0.51
▸ CASP5 P51878 1/20 0.51
▸ CASP7 P55210 1/20 0.51
▸ CASP9 P55211 1/20 0.51
▸ CASP6 P55212 1/20 0.51
▸ CASP8 Q14790 1/20 0.51
▸ CASP10 Q92851 1/20 0.51
▸ MMP2 P08253 5/20 0.50
▸ MMP8 P22894 4/20 0.50
▸ MMP9 P14780 3/20 0.50
▸ PCSK9 Q8NBP7 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30680479 0.92 ERAP2 (0.62) ERAP2EDNRAMAGI3IL1RNMMP1
SCHEMBL22366982 0.90 ERAP2 (0.67) ERAP2IL1RNMMP1ERAP1ECE1
SCHEMBL1877672 0.87 ERAP2 (0.64) ERAP2EDNRAMAGI3IL1RNERAP1
SCHEMBL1877671 0.87 ERAP2 (0.64) ERAP2EDNRAMAGI3IL1RNERAP1
SCHEMBL30571040 0.86 OPRM1 (0.57) ERAP2EDNRAMAGI3MMP1ECE1
SCHEMBL30051725 0.86 EDNRA (0.60) ERAP2EDNRAMAGI3IL1RNMMP1
SCHEMBL30051322 0.86 ECE1 (0.64) ERAP2MMP1ECE1MMP2MMP8
SCHEMBL29519902 0.86 MMP2 (0.61) ERAP2IL1RNMMP1ERAP1ECE1
SCHEMBL31258887 0.85 EDNRA (0.56) ERAP2EDNRAMAGI3IL1RNERAP1
SCHEMBL30123123 0.85 ERAP2 (0.76) ERAP2IL1RNMMP1ERAP1ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132222-A1 PROTEINS SPECIFIC FOR BAFF AND B7RP1 AND USES THEREOF AMGEN INC. (US) 2026-05-14 — — US disclosed
US-12600792-B2 Monoclonal antibodies and methods of use ELANCO TIERGESUNDHEIT AG (CH) 2026-04-14 — — US disclosed
US-12545746-B2 Anti-BCMA car antibodies, conjugates, and methods of use 2SEVENTY BIO, INC. (US) 2026-02-10 — — US disclosed
US-20260035480-A1 SICKLED BETA GLOBIN ANTIBODIES BLUEBIRD BIO INC (US) 2026-02-05 — — US disclosed
US-20250368956-A1 TGFBETA SIGNAL CONVERTOR REGENERON PHARMA (US) 2025-12-04 — — US disclosed
US-12479930-B2 Proteins specific for BAFF and B7RP1 and uses thereof AMGEN INC. (US) 2025-11-25 — — US disclosed
US-12454580-B2 FRB antibodies REGENERON PHARMACEUTICALS, INC. (US) 2025-10-28 — — US disclosed
EP-3689371-B1 PROTEINS SPECIFIC FOR BAFF AND B7RP1 AND USES THEREOF AMGEN INC (US) 2025-10-22 — — EP disclosed
US-12441792-B2 Antibodies specific for immunoglobulin-like transcript 3 (ILT3) and uses thereof MERCK SHARP & DOHME LLC (US) 2025-10-14 — — US disclosed
US-12435133-B2 Antibodies specific for immunoglobulin-like transcript 3 (ILT3) and uses thereof MERCK SHARP & DOHME LLC (US) 2025-10-07 — — US disclosed
EP-4014996-A1 ANTI-SIALYL TN CHIMERIC ANTIGEN RECEPTORS Helixmith Co., Ltd (KR) 2022-06-22 — — EP disclosed
US-11357849-B2 Anti-nucleolin antibodies MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2022-06-14 — — US disclosed
EP-3456344-B1 PROTEINS SPECIFIC FOR BAFF AND B7RP1 AND USES THEREOF AMGEN INC (US) 2022-05-04 — — EP disclosed
US-11319377-B2 Monoclonal antibodies and methods of use ELANCO TIERGESUNDHEIT AG (CH) 2022-05-03 — — US disclosed
US-11279769-B2 Anti-Sialyl Tn chimeric antigen receptors HELIXMITH CO., LTD (KR) 2022-03-22 — — US disclosed
CN-114206936-A Compositions and methods for treating cancer 2赛文缇生物公司 2022-03-18 — — CN disclosed
WO-2022046730-A2 BCMA CHIMERIC ANTIGEN RECEPTORS BLUEBIRD BIO, INC. (US) 2022-03-03 — — WO disclosed
US-20220034902-A1 METHOD FOR IDENTIFYING HIGH AFFINITY MONOCLONAL ANTIBODY HEAVY AND LIGHT CHAIN PAIRS FROM HIGH THROUGHPUT SCREENS OF B-CELL AND HYBRIDOMA LIBRARIES MERCK SHARP & DOHME CORP. (US) 2022-02-03 — — US disclosed
US-11236169-B2 Anti-DEspR monoclonal antibody targeted therapy and imaging for cancer and stroke TRUSTEES OF BOSTON UNIVERSITY (US) 2022-02-01 — — US disclosed
US-20220025042-A1 ANTIBODIES SPECIFIC FOR IMMUNOGLOBULIN-LIKE TRANSCRIPT 3 (ILT3) AND USES THEREOF MERCK SHARP & DOHME CORP. (US) 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132222-A1 PROTEINS SPECIFIC FOR BAFF AND B7RP1 AND USES THEREOF SSB, IGSF11, CD22 ERAP2 2159/4885EDNRA 1741/4885MAGI3 4591/4885
US-12600792-B2 Monoclonal antibodies and methods of use IGSF11, IGLV6-57, CDY1; CDY1B ERAP2 4477/4885EDNRA 4428/4885MAGI3 4108/4885
US-12545746-B2 Anti-BCMA car antibodies, conjugates, and methods of use CD47, RBM25, CD22 ERAP2 1524/4885EDNRA 1291/4885MAGI3 4236/4885
US-20260035480-A1 SICKLED BETA GLOBIN ANTIBODIES HBB, HBZ, HBG2 ERAP2 1519/4885EDNRA 2982/4885MAGI3 4585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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