SCHEMBL29359379

SCHEMBL29359379

CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCCCC(=O)O

nearest known ligand 0.92

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.86
▸ CHAT P28329 2/20 0.82
▸ EP300 Q09472 3/20 0.81
▸ KAT5 Q92993 2/20 0.81
▸ AURKA O14965 2/20 0.81
▸ KAT2B Q92831 1/20 0.81
▸ CREBBP Q92793 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29359732 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL29359942 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
Succinic Acid SCHEMBL29713569 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL851130 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL15984379 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL29652062 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL29403288 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL29424683 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL29652056 0.99 NAA50 (0.85) NAA50CHATEP300KAT5AURKA
SCHEMBL29351815 0.99 NAA50 (0.86) NAA50CHATEP300KAT5AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3362567-B1 GENETICALLY ENGINEERED BACTERIUM COMPRISING ENERGY-GENERATING FERMENTATION PATHWAY LANZATECH NZ INC (US) 2026-05-06 — — EP claimed
US-12577594-B2 Engineered microorganisms and methods for improved aldehyde dehydrogenase activity GENOMATICA, INC. (US) 2026-03-17 — — US claimed
US-12577591-B2 Microorganisms and methods for increasing co-factors GENOMATICA, INC. (US) 2026-03-17 — — US claimed
US-20260035705-A1 ENGINEERED MICROORGANISMS WITH G3P ->3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY AGAIN BIO APS (DK) 2026-02-05 — — US claimed
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES AGAIN BIO APS (DK) 2026-01-29 — — US claimed
US-12529078-B2 Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis GENOMATICA, INC. (US) 2026-01-20 — — US claimed
US-12503711-B2 Method of producing and processing diamines to a diamine free base using a carbonate intermediate and an engineered microorganism GENOMATICA, INC. (US) 2025-12-23 — — US claimed
EP-4642908-A2 LIGASE AND DEHYDROGENASE VARIANTS AND METHODS OF USE Genomatica, Inc. (US) 2025-11-05 — — EP claimed
US-12275979-B2 Gene-modified microorganism for producing 3-hydroxyadipic acid, alpha-hydromuconic acid, and/or adipic acid, and production method for said chemical products TORAY INDUSTRIES, INC. (JP) 2025-04-15 — — US claimed
WO-2025063258-A1 GENE-MODIFIED MICROORGANISM FOR PRODUCING α-HYDROMUCONIC ACID AND/OR ADIPIC ACID AND METHOD FOR PRODUCING SAID CHEMICAL PRODUCT 東レ株式会社 2025-03-27 — — WO claimed
CN-114901815-A Microorganisms and methods for increasing cofactors 基因组股份公司 2022-08-12 — — CN claimed
US-20220235385-A1 ENGINEERED MICROORGANISMS AND METHODS FOR IMPROVED ALDEHYDE DEHYDROGENASE ACTIVITY AGAIN BIO APS (DK) 2022-07-28 — — US claimed
CN-114728871-A Microorganisms and methods for reducing by-products 基因组股份公司 2022-07-08 — — CN claimed
US-20220213514-A1 GENETICALLY MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYHEXANEDIOIC ACID, (E)-HEX-2-ENEDIOIC ACID AND/OR HEXANEDIOIC ACID, AND PRODUCTION METHOD FOR SAID CHEMICALS TORAY INDUSTRIES, INC. (JP) 2022-07-07 — — US claimed
US-20220177895-A1 ENGINEERED MICROORGANISMS WITH G3P -> 3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY AGAIN BIO APS (DK) 2022-06-09 — — US claimed
CN-114341344-A Engineered microorganisms and methods for improving aldehyde dehydrogenase activity 基因组股份公司 2022-04-12 — — CN claimed
US-11293026-B2 Microorganisms for the production of adipic acid and other compounds GENOMATICA, INC. (US) 2022-04-05 — — US claimed
CN-114269908-A Engineered trans-enoyl COA reductase and preparation method and using method thereof 基因组股份公司 2022-04-01 — — CN claimed
EP-3967762-A1 GENETICALLY MODIFIED MICROORGANISM FOR PRODUCING 3-HYDROXYHEXANEDIOIC ACID, (E)-HEX-2-ENEDIOIC ACID AND/OR HEXANEDIOIC ACID, AND PRODUCTION METHOD FOR SAID CHEMICALS Toray Industries, Inc. (JP) 2022-03-16 — — EP claimed
EP-3959327-A1 ENGINEERED TRANS-ENOYL COA REDUCTASE AND METHODS OF MAKING AND USING Genomatica, Inc. (US) 2022-03-02 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12529078-B2 Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis ALDOA, FDPS, DERA NAA50 298/4885CHAT 1363/4885EP300 1390/4885
US-12577594-B2 Engineered microorganisms and methods for improved aldehyde dehydrogenase activity ACADM, ALDH7A1, ADSL NAA50 211/4885CHAT 350/4885EP300 1233/4885
US-20260028651-A1 METHOD OF PRODUCING & PROCESSING DIAMINES DDC, DAO, ODC1 NAA50 69/4885CHAT 77/4885EP300 1948/4885
US-12577591-B2 Microorganisms and methods for increasing co-factors ABAT, HADHB, MMAB NAA50 278/4885CHAT 1499/4885EP300 3766/4885
US-20260035705-A1 ENGINEERED MICROORGANISMS WITH G3P ->3PG ENZYME AND/OR FRUCTOSE-1,6-BISPHOSPHATASE INCLUDING THOSE HAVING SYNTHETIC OR ENHANCED METHYLOTROPHY ME1, FBP1, ME3 NAA50 2772/4885CHAT 1142/4885EP300 3078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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