SCHEMBL29360000

SCHEMBL29360000

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](N)CCCCN)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 3/20 0.51
▸ REN P00797 3/20 0.49
▸ OPRM1 P35372 1/20 0.49
▸ OPRD1 P41143 1/20 0.49
▸ OPRK1 P41145 1/20 0.49
▸ CXCR4 P61073 3/20 0.49
▸ SLC15A2 Q16348 1/20 0.49
▸ OPRL1 P41146 2/20 0.48
▸ GHSR Q92847 3/20 0.47
▸ VIPR1 P32241 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31256987 0.88 OPRD1 (0.61) OPRM1OPRD1OPRK1
Kifgslafl SCHEMBL29356758 0.81 BACE1 (0.57) OPRM1OPRD1OPRK1
SCHEMBL31433367 0.81 OPRM1 (0.49) OPRM1OPRD1OPRK1OPRL1
SCHEMBL29623290 0.81 VIPR2 (0.65) GHSRVIPR1
SCHEMBL29419673 0.80 OPRD1 (0.45) OPRM1OPRD1OPRK1
SCHEMBL31257081 0.80 OPRD1 (0.64) OPRM1OPRD1OPRK1
SCHEMBL18854322 0.79 IL23R (0.60) IL23RRENGHSR
SCHEMBL30799723 0.79 OPRK1 (0.57) OPRM1OPRD1OPRK1
SCHEMBL38662535 0.79 OPRM1 (0.61) OPRM1OPRD1OPRK1
SCHEMBL31257045 0.79 OPRM1 (0.56) OPRM1OPRD1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661876-A1 METABOLIC INHIBITORS AND METHODS OF MAKING AND USING THEREOF University of Miami (US) 2025-12-17 — — EP claimed
US-20250242086-A1 THERAPEUTIC BIOMATERIAL THAT ATTENUATES THE FOREIGN BODY RESPONSE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2025-07-31 — — US claimed
WO-2024168133-A1 METABOLIC INHIBITORS AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF MIAMI (US) 2024-08-15 — — WO claimed
WO-2023219948-A1 THERAPEUTIC BIOMATERIAL THAT ATTENUATES THE FOREIGN BODY RESPONSE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2023-11-16 — — WO claimed
EP-3943085-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2022-01-26 — — EP claimed
US-12534536-B2 Natural killer cells expressing a chimeric antigen receptor that binds CD38 ONK THERAPEUTICS LIMITED (IE) 2026-01-27 — — US disclosed
EP-4674268-A2 INSECTICIDAL PROTEINS FROM PLANTS AND METHODS FOR THEIR USE Pioneer Hi-Bred International, Inc. (US) 2026-01-07 — — EP disclosed
EP-4661876-A1 METABOLIC INHIBITORS AND METHODS OF MAKING AND USING THEREOF University of Miami (US) 2025-12-17 — — EP disclosed
EP-3764798-B1 INSECTICIDAL PROTEINS FROM PLANTS AND METHODS FOR THEIR USE PIONEER HI BRED INT (US) 2025-12-17 — — EP disclosed
US-20250327089-A1 NOVEL INSECTICIDAL PROTEINS FROM PLANTS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-10-23 — — US disclosed
US-20250242086-A1 THERAPEUTIC BIOMATERIAL THAT ATTENUATES THE FOREIGN BODY RESPONSE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2025-07-31 — — US disclosed
EP-3635373-B1 ANALYSIS OF SINGLE CELL MECHANICAL PHENOTYPING FOR METASTATIC DETECTION UNIV MARYLAND (US) 2025-07-30 — — EP disclosed
US-20220305129-A1 CONJUGATES OF HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS ASCENDIS PHARMA A/S (DK) 2022-09-29 — — US disclosed
CN-114763376-A Insecticidal proteins and methods of use thereof 先锋国际良种公司 2022-07-19 — — CN disclosed
EP-3895712-B1 ENGINEERED NATURAL KILLER CELLS AND USES THEREOF ONK THERAPEUTICS LTD (IE) 2022-06-22 — — EP disclosed
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 — — EP disclosed
EP-3986477-A1 CONJUGATES OF pi-ELECTRON-PAIR-DONATING HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS Ascendis Pharma A/S (DK) 2022-04-27 — — EP disclosed
EP-3986472-A1 CONJUGATES OF HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS Ascendis Pharma A/S (DK) 2022-04-27 — — EP disclosed
US-20220072013-A1 Pharmaceutical Combinations for the Treatment of Cancer CA*TX, INC. 2022-03-10 — — US disclosed
EP-3943085-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220305129-A1 CONJUGATES OF HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS NQO1, ABCB1, NCL IL23R 1691/4885REN 593/4885OPRM1 90/4885
US-20220072013-A1 Pharmaceutical Combinations for the Treatment of Cancer APC, TP53, VHL IL23R 1567/4885REN 3694/4885OPRM1 4771/4885
US-12534536-B2 Natural killer cells expressing a chimeric antigen receptor that binds CD38 TNFRSF9, TNFRSF1A, CD40 IL23R 54/4885REN 3987/4885OPRM1 3513/4885
US-20250327089-A1 NOVEL INSECTICIDAL PROTEINS FROM PLANTS RNGTT, CACYBP, CNBP IL23R 4774/4885REN 4435/4885OPRM1 4629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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