Sugi Predict

Sugi Predict / Compounds / SCHEMBL29366333

SCHEMBL29366333

SCHEMBL29366333

C=C(C[C@H](NC(=O)c1ccc(CCc2cnc3nc(N)nc(N)c3n2)cc1)C(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHFR P00374 13/20 1.00
▸ FOLR1 P15328 2/20 0.54
▸ SLC19A1 P41440 2/20 0.54
▸ SLC46A1 Q96NT5 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ TLR4 O00206 1/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ ALDH1A1 P00352 1/20 0.54
▸ LMNA P02545 1/20 0.54
▸ TP53 P04637 1/20 0.54
▸ TYMS P04818 1/20 0.54
▸ GLA P06280 1/20 0.54
▸ POLB P06746 1/20 0.54
▸ HMGB1 P09429 1/20 0.54
▸ MAPT P10636 1/20 0.54
▸ FOLR2 P14207 1/20 0.54
▸ HPGD P15428 1/20 0.54
▸ ALOX15 P16050 1/20 0.54
▸ ALOX12 P18054 1/20 0.54
▸ GART P22102 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1065136 1.00 DHFR (1.00) DHFRFOLR1SLC19A1SLC46A1KDM4E
SCHEMBL14314 1.00 DHFR (1.00) DHFRFOLR1SLC19A1SLC46A1KDM4E
SCHEMBL29430165 0.85 DHFR (1.00) DHFRFOLR1SLC19A1SLC46A1KDM4E
SCHEMBL15700766 0.85 DHFR (1.00) DHFRFOLR1SLC19A1SLC46A1KDM4E
SCHEMBL7081697 0.85 DHFR (1.00) DHFRFOLR1SLC19A1SLC46A1KDM4E
SCHEMBL25725292 0.85 DHFR (0.82) DHFRFOLR1SLC19A1SLC46A1KDM4E
SCHEMBL24192605 0.81 DHFR (0.75) DHFR
SCHEMBL24344801 0.80 DHFR (0.74) DHFRFOLR1SLC19A1SLC46A1KDM4E
SCHEMBL15530110 0.80 DHFR (0.90) DHFRFOLR1SLC19A1SLC46A1KDM4E
SCHEMBL24192971 0.80 DHFR (0.73) DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119832220-B Low-illumination target detection method based on multidimensional attention mechanism 安徽中科大国祯信息科技有限责任公司 2025-06-03 — — CN claimed
CN-119832220-A Low-illumination target detection method based on multidimensional attention mechanism 安徽中科大国祯信息科技有限责任公司 2025-04-15 — — CN claimed
CN-119671929-A Power transmission line icing detection method based on wide-area perception dynamic convolution model 国网陕西省电力有限公司电力科学研究院 2025-03-21 — — CN claimed
CN-118799657-B Method and system for classifying non-magnetic metals of scraped car 昆明理工大学 2024-12-03 — — CN claimed
CN-118799657-A Method and system for classifying non-magnetic metals of scraped car 昆明理工大学 2024-10-18 — — CN claimed
CN-118800363-A Pilot active molecule generation and screening method based on artificial intelligence fragmentation technology 南通大学附属医院 2024-10-18 — — CN claimed
CN-118470328-A Multi-dimensional attention semantic segmentation method and system for remote sensing image 太原科技大学 2024-08-09 — — CN claimed
CN-117409291-A Target detection method based on refinement feature enhancement network 河南科技大学 2024-01-16 — — CN claimed
CN-116129115-A Image semantic segmentation method based on dynamic convolution attention 北京工业大学 2023-05-16 — — CN claimed
CN-115527123-B Land cover remote sensing monitoring method based on multisource feature fusion 河北省科学院地理科学研究所 2023-05-05 — — CN claimed
CN-115546647-A Semantic segmentation model based on remote sensing image 河北省科学院地理科学研究所 2022-12-30 — — CN claimed
CN-115527123-A Land cover remote sensing monitoring method based on multi-source feature fusion 河北省科学院地理科学研究所 2022-12-27 — — CN claimed
CN-115114053-A Hard disk reliability test method, system, storage medium and equipment 苏州浪潮智能科技有限公司 2022-09-27 — — CN claimed
EP-3964206-A1 COMPOUNDS FOR THE TREATMENT OF COVID-19 Dompe' Farmaceutici S.P.A. (IT) 2022-03-09 — — EP claimed
US-20260146082-A1 BISPECIFIC ANTI-MYOSTATIN AND ACTIVIN A ANTIBODY OR ANTIGEN BINDING FRAGMENTS THEREOF IBIO, INC. (US) 2026-05-28 — — US disclosed
US-20260144674-A1 Apparatus and Methods for Drug Delivery Using Microneedles CLEARSIDE BIOMEDICAL, INC. (US) 2026-05-28 — — US disclosed
CN-119671929-B Power transmission line icing detection method based on wide-area perception dynamic convolution model 国网陕西省电力有限公司电力科学研究院 2026-05-08 — — CN disclosed
EP-3964206-A1 COMPOUNDS FOR THE TREATMENT OF COVID-19 Dompe' Farmaceutici S.P.A. (IT) 2022-03-09 — — EP disclosed
US-11260126-B2 Acoustic driven drug delivery systems UNIVERSITY OF OTAGO (NZ) 2022-03-01 — — US disclosed
CN-110177527-B Device and method for adjusting insertion depth of needle for medicament delivery 科尼尔赛德生物医学公司 2022-02-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144674-A1 Apparatus and Methods for Drug Delivery Using Microneedles PROKR2, SLC10A2, GLP1R DHFR 3293/4885FOLR1 183/4885SLC19A1 267/4885
US-11260126-B2 Acoustic driven drug delivery systems LSS, LIPA, MTREX DHFR 1340/4885FOLR1 863/4885SLC19A1 1654/4885
US-20260146082-A1 BISPECIFIC ANTI-MYOSTATIN AND ACTIVIN A ANTIBODY OR ANTIGEN BINDING FRAGMENTS THEREOF MSTN, MST1R, MYOF DHFR 3352/4885FOLR1 1240/4885SLC19A1 4434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.