Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | RHOC | P08134 | 1/20 | 0.32 |
| ▸ | RHOA | P61586 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Afoxolaner SCHEMBL18054743 | 1.00 | PTGES (0.33) | PTGESTACR1RHOCRHOAP2RX1 | |
| Esafoxolaner SCHEMBL29413811 | 1.00 | PTGES (0.33) | PTGESTACR1RHOCRHOAP2RX1 | |
| Afoxolaner SCHEMBL29358921 | 1.00 | PTGES (0.33) | PTGESTACR1RHOCRHOAP2RX1 | |
| Afoxolaner SCHEMBL119580 | 1.00 | PTGES (0.33) | PTGESTACR1RHOCRHOAP2RX1 | |
| Esafoxolaner SCHEMBL18054742 | 1.00 | PTGES (0.33) | PTGESTACR1RHOCRHOAP2RX1 | |
| SCHEMBL3113195 | 0.94 | PTGES (0.32) | PTGESHPGDPOLB | |
| SCHEMBL20117288 | 0.94 | PTGES (0.32) | PTGESHPGDPOLB | |
| SCHEMBL3110704 | 0.94 | TACR1 (0.34) | PTGESTACR1RHOCRHOAP2RX1 | |
| SCHEMBL29416682 | 0.94 | PTGES (0.32) | PTGESHPGDPOLB | |
| SCHEMBL119082 | 0.94 | PTGES (0.32) | PTGESHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4430947-A1 | THERAPEUTIC USE OF ISOXAZOLINE COMPOUNDS, COMPOSITION OF ISOXAZOLINE COMPOUNDS AND KIT FOR THERAPEUTIC USE | Przedsiebiorstwo Wielobranzowe "Vet-Agro" Sp. Z O.O. (PL) | 2024-09-18 | — | — | EP | claimed |
| EP-4188094-A1 | A PESTICIDALLY ACTIVE MIXTURE COMPRISING PYRAZOLOPYRIDINE ANTHRANILAMIDE COMPOUND, OXIDES OR SALTS THEREOF | PI Industries Ltd. (IN) | 2023-06-07 | — | — | EP | claimed |
| EP-4175476-A1 | A PESTICIDALLY ACTIVE MIXTURE COMPRISING THIETANYLOXY COMPOUND, OXIDES OR SALTS THEREOF | PI Industries Ltd. (IN) | 2023-05-10 | — | — | EP | claimed |
| WO-2022243810-A1 | NOVEL AGROCHEMICAL COMPOSITION COMPRISING PIPERIDINE THIAZOLE COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2022-11-24 | — | — | WO | claimed |
| WO-2022130188-A1 | AGROCHEMICAL COMPOSITION COMPRISING PIPERIDINE THIAZOLE COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2022-06-23 | — | — | WO | claimed |
| CN-108685894-B | Soft chewable pharmaceutical product | 英特维特国际股份有限公司 | 2022-04-26 | — | — | CN | claimed |
| WO-2022023931-A1 | A PESTICIDALLY ACTIVE MIXTURE COMPRISING PYRAZOLOPYRIDINE ANTHRANILAMIDE COMPOUND, OXIDES OR SALTS THEREOF | PI INDUSTRIES LTD (IN) | 2022-02-03 | — | — | WO | claimed |
| US-12616677-B2 | Injectable pharmaceutical compositions and uses thereof | INTERVET INC. (US) | 2026-05-05 | — | — | US | disclosed |
| WO-2026041786-A1 | INJECTABLE VETERINARY COMPOSITION AND USES THEREOF | INTERVET INTERNATIONAL B.V. (NL) | 2026-02-26 | — | — | WO | disclosed |
| EP-4680579-A1 | DEGRADATION OF ISOXAZOLINES IN OZONATED SEA WATER | Zoetis Services LLC (US) | 2026-01-21 | — | — | EP | disclosed |
| US-12390450-B2 | Antiparasitic pour-on compositions | INTERVET INC. (US) | 2025-08-19 | — | — | US | disclosed |
| EP-4580627-A1 | TREATMENT OF FASCIOLOSIS | Intervet International B.V. (NL) | 2025-07-09 | — | — | EP | disclosed |
| EP-4559482-A2 | ANTIPARASITIC POUR-ON COMPOSITIONS | Intervet International B.V. (NL) | 2025-05-28 | — | — | EP | disclosed |
| WO-2022130188-A1 | AGROCHEMICAL COMPOSITION COMPRISING PIPERIDINE THIAZOLE COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2022-06-23 | — | — | WO | disclosed |
| EP-3313400-B1 | ISOXAZOLINE SOLUTION CONTAINING VITAMIN E FOR USE WITH SANITIZED DRINKING WATER | INTERVET INT BV (NL) | 2022-06-15 | — | — | EP | disclosed |
| CN-114573573-A | Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-108685894-B | Soft chewable pharmaceutical product | 英特维特国际股份有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-110897889-B | Manufacture of semi-plastic pharmaceutical dosage units | 英特维特国际股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| EP-3962448-A1 | INJECTABLE PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Intervet International B.V. (NL) | 2022-03-09 | — | — | EP | disclosed |
| CN-109068651-B | Antiparasitic isoxazoline compounds, long-acting injectable formulations containing them, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2022-03-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12390450-B2 | Antiparasitic pour-on compositions | PIGS, ARG1, ARG2 | PTGES 966/4885TACR1 3519/4885RHOC 2225/4885 |
| US-12616677-B2 | Injectable pharmaceutical compositions and uses thereof | EPX, P2RX7, MTX1 | PTGES 503/4885TACR1 2622/4885RHOC 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.