SCHEMBL29375073

SCHEMBL29375073

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@@H]1CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)NCC(=O)N[C@H](CCCCN)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]1CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@H]2CSSC[C@H](C(N)=O)NC(=O)[C@@H](CCCCN)NC(=O)CNC(=O)[C@@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC2=O)[C@@H](C)O)NC1=O

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPR1 P16066 1/20 0.59
NPR3 P17342 1/20 0.59
BCL2L1 Q07817 2/20 0.58
BAD Q92934 2/20 0.58
CACNA1B Q00975 1/20 0.56
RXFP4 Q8TDU9 5/20 0.55
RXFP3 Q9NSD7 5/20 0.55
KCNMA1 Q12791 1/20 0.54
KCNMB4 Q86W47 1/20 0.54
F11 P03951 2/20 0.53
RXFP1 Q9HBX9 1/20 0.52
NPY2R P49146 2/20 0.50
TERF2IP Q9NYB0 2/20 0.50
CSNK2A2 P19784 1/20 0.49
CSNK2B P67870 1/20 0.49
CSNK2A1 P68400 1/20 0.49
CSNK2A3 Q8NEV1 1/20 0.49
BECN1 Q14457 1/20 0.49
TNFSF11 O14788 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15186042 0.77 BCL2L1 (0.61) NPR1NPR3BCL2L1BADCACNA1B
Carperitide SCHEMBL218549 0.77 NPR1 (0.94) NPR1NPR3BCL2L1BADRXFP4
SCHEMBL29376235 0.74 NPR1 (0.88) NPR1NPR3RXFP4RXFP3KCNMA1
Acetic Acid SCHEMBL29363649 0.74 NPR1 (0.87) NPR1NPR3CACNA1BKCNMA1KCNMB4
Ularitide SCHEMBL27908491 0.73 NPR1 (0.79) NPR1NPR3RXFP4RXFP3F11
SCHEMBL29711548 0.73 NPR1 (0.86) NPR1NPR3RXFP4RXFP3KCNMA1
Hydrochloric Acid SCHEMBL29495482 0.72 NPR1 (0.85) NPR1NPR3RXFP4RXFP3KCNMA1
SCHEMBL29352842 0.72 BECN1 (0.63) NPR1NPR3RXFP4RXFP3KCNMA1
Ziconotide SCHEMBL29369952 0.72 CACNA1B (1.00) NPR1NPR3CACNA1B
Ziconotide SCHEMBL676878 0.72 CACNA1B (1.00) NPR1NPR3CACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713019-A2 CPG CONJUGATES AND METHODS OF USE The Board of Trustees of the Leland Stanford Junior University (US) 2026-03-25 EP claimed
CN-118949049-B Medicine assembly and preparation method and application thereof 国家纳米科学中心 2025-02-21 CN claimed
CN-119212689-A Nicotinic acetylcholine receptor antagonists/blockers for increasing dopamine 张燕峰 2024-12-27 CN claimed
WO-2024238677-A2 CPG CONJUGATES AND METHODS OF USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-11-21 WO claimed
CN-115353555-B Quaternized chitosan oligosaccharide-mu-conotoxin conjugate as well as preparation method and application thereof 山东大学 2024-04-30 CN claimed
CN-114573674-B Alpha 9 alpha 10nAChR inhibitory active peptide and application thereof 中国海洋大学 2023-11-14 CN claimed
WO-2023212244-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS, INC. (US) 2023-11-02 WO claimed
CN-116836255-A Chemical synthesis preparation method of mu-conotoxin peptide 广州森升生物科技有限公司 2023-10-03 CN claimed
CN-116392602-A Amphiphilic polypeptide carrier and application thereof 国家纳米科学中心 2023-07-07 CN claimed
CN-114853864-B nAChR receptor alpha 3 beta 2 subtype inhibition inactivation type blocking agent, and preparation method and application thereof 海南大学 2023-06-20 CN claimed
CN-110981967-B Dimer of alpha-conotoxin Mr1.1, synthetic method and application 中国海洋大学 2022-10-14 CN claimed
US-20220257785-A1 KNOTTIN-IMMUNOSTIMULANT CONJUGATES AND RELATED COMPOSITIONS AND METHODS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2022-08-18 US claimed
EP-4037709-A1 KNOTTIN-IMMUNOSTIMULANT CONJUGATES AND RELATED COMPOSITIONS AND METHODS The Board of Trustees of the Leland Stanford Junior University (US) 2022-08-10 EP claimed
CN-114585382-A Kink-immunostimulatory conjugates and related compositions and methods 小利兰·斯坦福大学理事会 2022-06-03 CN claimed
EP-3972647-A1 DRUG CONJUGATES AND METHODS OF USING SAME The Board Of Trustees Of The Leland Stanford Junior University (US) 2022-03-30 EP claimed
US-20260130908-A1 METHODS AND COMPOUNDS MODIFYING MITOCHONDRIAL FUNCTION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV (US) 2026-05-14 US disclosed
EP-4713019-A2 CPG CONJUGATES AND METHODS OF USE The Board of Trustees of the Leland Stanford Junior University (US) 2026-03-25 EP disclosed
US-20220040095-A1 AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS DOMPÉ FARMACEUTICI S.P.A. (IT) 2022-02-10 US disclosed
EP-3946411-A1 COMPOSITIONS AND METHODS FOR GENETICALLY-ENCODED HIGH VOLTAGE-ACTIVATED CALCIUM CHANNEL BLOCKERS USING ENGINEERED UBIQUITIN LIGASES The Trustees of Columbia University in the City of New York (US) 2022-02-09 EP disclosed
US-20220031631-A1 HIGH-PURITY PEG LIPIDS AND USES THEREOF MODERNATX, INC. (US) 2022-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220031631-A1 HIGH-PURITY PEG LIPIDS AND USES THEREOF LIPA, HDLBP, PLTP NPR1 2626/4885NPR3 2865/4885BCL2L1 2528/4885
US-20260130908-A1 METHODS AND COMPOUNDS MODIFYING MITOCHONDRIAL FUNCTION SHMT2, NLN, TFAM NPR1 3476/4885NPR3 3994/4885BCL2L1 273/4885
US-20220040095-A1 AURIS FORMULATIONS FOR TREATING OTIC DISEASES AND CONDITIONS OTC, AQP4, SLC26A4 NPR1 554/4885NPR3 1316/4885BCL2L1 3753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.