SCHEMBL29352842

SCHEMBL29352842

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H]1CSSC[C@@H](C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC1=O)C(C)C

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BECN1 Q14457 11/20 0.63
KCNMA1 Q12791 1/20 0.60
KCNMB4 Q86W47 1/20 0.60
INSR P06213 1/20 0.60
ALB P02768 1/20 0.59
CSNK2A2 P19784 1/20 0.58
CSNK2B P67870 1/20 0.58
CSNK2A1 P68400 1/20 0.58
CSNK2A3 Q8NEV1 1/20 0.58
NPR1 P16066 1/20 0.57
NPR3 P17342 1/20 0.57
RXFP1 Q9HBX9 1/20 0.57
RXFP4 Q8TDU9 3/20 0.56
RXFP3 Q9NSD7 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17236232 0.95 BECN1 (0.70) BECN1KCNMA1KCNMB4INSRALB
SCHEMBL14654850 0.92 BECN1 (0.67) BECN1KCNMA1KCNMB4INSRALB
SCHEMBL17236230 0.91 BECN1 (0.66) BECN1KCNMA1KCNMB4INSRALB
SCHEMBL8991433 0.91 BECN1 (0.63) BECN1KCNMA1KCNMB4INSRALB
SCHEMBL8991534 0.91 BECN1 (0.59) BECN1KCNMA1KCNMB4INSRALB
SCHEMBL29607029 0.80 CSNK2A2 (0.67) BECN1KCNMA1KCNMB4INSRCSNK2A2
Iseganan SCHEMBL29378977 0.79 CTSG (0.56) BECN1KCNMA1KCNMB4ALBCSNK2A2
Protegrin 1 SCHEMBL29352276 0.78 F12 (0.54) BECN1KCNMA1KCNMB4
Iseganan SCHEMBL29420585 0.78 CTSG (0.55) BECN1KCNMA1KCNMB4ALBCSNK2A2
SCHEMBL14840198 0.78 INSR (0.93) KCNMA1KCNMB4INSRCSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
EP-3787631-B1 MODULATORS OF ORPHAN NUCLEAR RECEPTORS FOR NASH AND OTHER METABOLIC DISORDERS UNIV EMORY (US) 2025-09-10 EP claimed
CN-118209669-A Solid phase extraction-liquid chromatography-mass spectrometry detection method for small peptide substances in dry blood spots 北京体育大学 2024-06-18 CN claimed
CN-116973466-A Solid phase extraction-liquid chromatography-mass spectrometry detection method for small peptide substances 北京体育大学 2023-10-31 CN claimed
CN-107614695-B Methods of treating obesity and non-alcoholic fatty liver disease or non-alcoholic steatohepatitis with glucagon receptor antagonist antibodies 瑞美德生物医药科技有限公司 2022-01-25 CN claimed
EP-4743083-A1 METHODS OF TREATING FIBROTIC LIVER DISEASES OR CONDITIONS WITH INDEGLITAZAR Pleiogenix Inc. (US) 2026-05-20 EP disclosed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 US disclosed
US-12611401-B2 Combinations comprising benzodioxol as GLP-1R agonists for use in the treatment of NASH/NAFLD and related diseases PFIZER INC. (US) 2026-04-28 US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US disclosed
CN-121851142-A Synthesis method of AOD-9604 polypeptide 杭州贝普泰生物医药有限公司 2026-04-14 CN disclosed
CN-121851142-A Synthesis method of AOD-9604 polypeptide 杭州贝普泰生物医药有限公司 2026-04-14 CN disclosed
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 EP disclosed
US-20220064181-A1 SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF GILEAD APOLLO, LLC 2022-03-03 US disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 CN disclosed
US-11254660-B2 Combinations for treatment of NASH/NAFLD and related diseases PFIZER INC. (US) 2022-02-22 US disclosed
US-20220047605-A1 SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF SOLENO THERAPEUTICS, INC. 2022-02-17 US disclosed
CN-111630058-B Glucopyranosyl derivative and use thereof 广东东阳光药业有限公司 2022-02-15 CN disclosed
US-20220023299-A1 Combinations For Treatment Of NASH/NAFLD And Related Diseases PFIZER INC. (US) 2022-01-27 US disclosed
CN-107614695-B Methods of treating obesity and non-alcoholic fatty liver disease or non-alcoholic steatohepatitis with glucagon receptor antagonist antibodies 瑞美德生物医药科技有限公司 2022-01-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS BECN1 3953/4885KCNMA1 3646/4885KCNMB4 3775/4885
US-20220047605-A1 SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF KCNJ1, KCNJ11, KCNJ2 BECN1 1983/4885KCNMA1 44/4885KCNMB4 63/4885
US-20220064181-A1 SOLID FORMS OF A THIENOPYRIMIDINEDIONE ACC INHIBITOR AND METHODS FOR PRODUCTION THEREOF ACACA, ACACB, COASY BECN1 2061/4885KCNMA1 4425/4885KCNMB4 4548/4885
US-11254660-B2 Combinations for treatment of NASH/NAFLD and related diseases FABP1, PPARG, GOT2 BECN1 205/4885KCNMA1 4601/4885KCNMB4 4342/4885
US-12611401-B2 Combinations comprising benzodioxol as GLP-1R agonists for use in the treatment of NASH/NAFLD and related diseases GLP1R, GCKR, GPR119 BECN1 1454/4885KCNMA1 2040/4885KCNMB4 2659/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT BECN1 3634/4885KCNMA1 3844/4885KCNMB4 2069/4885
US-20220023299-A1 Combinations For Treatment Of NASH/NAFLD And Related Diseases FABP1, PPARG, GOT2 BECN1 205/4885KCNMA1 4601/4885KCNMB4 4342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.