SCHEMBL29378142

SCHEMBL29378142

CN(C)c1cccc(N(C)C)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
NSD2 O96028 1/20 0.41
ALDH1A1 P00352 1/20 0.41
EGFR P00533 1/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HTR6 P50406 1/20 0.37
PDK2 Q15119 1/20 0.35
ROCK2 O75116 1/20 0.33
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14736169 1.00 MAPT (0.41) MAPTNSD2ALDH1A1EGFRLMNA
SCHEMBL19469287 0.96 NSD2 (0.38) MAPTNSD2ALDH1A1EGFRLMNA
SCHEMBL14117087 0.92 LMNA (0.37) MAPTNSD2ALDH1A1EGFRLMNA
SCHEMBL17606883 0.91 MAPK1 (0.40) MAPTNSD2ALDH1A1EGFRLMNA
SCHEMBL27042345 0.90 NSD2 (0.40) MAPTNSD2ALDH1A1EGFRLMNA
SCHEMBL32667778 0.90 NSD2 (0.40) MAPTNSD2ALDH1A1EGFRLMNA
SCHEMBL29353225 0.88 HTR6 (0.36) MAPTNSD2ALDH1A1EGFRLMNA
SCHEMBL29354371 0.88 HTR6 (0.36) MAPTNSD2ALDH1A1EGFRLMNA
SCHEMBL21788 0.88 HTR6 (0.36) MAPTNSD2ALDH1A1EGFRLMNA
SCHEMBL4988734 0.86 HTR6 (0.34) MAPTNSD2ALDH1A1EGFRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 629 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062374-A1 PROCESS FOR THE PREPARATION OF A BENZENE DERIVATIVE MELETIOS THERAPEUTICS (FR) 2026-03-05 US claimed
US-20250388564-A1 METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS EDGEWISE THERAPEUTICS INC (US) 2025-12-25 US claimed
EP-4594306-A1 SYNTHESIS METHODS AND INTERMEDIATES FOR THE PRODUCTION OF REMIBRUTINIB Novartis AG (CH) 2025-08-06 EP claimed
EP-4568984-A1 PROCESS FOR MANUFACTURING AN ANTIBIOTIC MACROCYCLIC PEPTIDE F. Hoffmann-La Roche AG (CH) 2025-06-18 EP claimed
CN-119998265-A Synthetic methods and intermediates for the production of rebaudinib 诺华股份有限公司 2025-05-13 CN claimed
CN-119677765-A Method for producing antibiotic macrocyclic peptides 豪夫迈·罗氏有限公司 2025-03-21 CN claimed
EP-4522599-A1 METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS EDGEWISE THERAPEUTICS, INC. (US) 2025-03-19 EP claimed
CN-119317621-A Process for preparing pyridazinone compounds 艾知怀斯治疗学公司 2025-01-14 CN claimed
EP-4038071-B1 PROCESS FOR PREPARING AN ACTIVIN RECEPTOR-LIKE KINASE INHIBITOR BLUEPRINT MEDICINES CORP (US) 2024-12-18 EP claimed
US-20240300922-A1 PROCESS FOR PREPARING EGFR INHIBITORS BLUEPRINT MEDICINES CORPORATION 2024-09-12 US claimed
WO-2023220180-A1 METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS EDGEWISE THERAPEUTICS, INC. (US) 2023-11-16 WO claimed
EP-4267591-A2 ORGANOMETALLIC COMPOUNDS Umicore AG & Co. KG (DE) 2023-11-01 EP claimed
CN-116802187-A Organometallic compounds 优米科尔股份公司及两合公司 2023-09-22 CN claimed
CN-116655634-A N6 chiral cyclic compound and preparation method and application thereof 中国科学院化学研究所 2023-08-29 CN claimed
WO-2023102255-A1 PEPTIDE-ENCODED LIBRARIES OF SMALL MOLECULES FOR DE NOVO DRUG DISCOVERY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-06-08 WO claimed
WO-2022271801-A1 PROCESS FOR PREPARING EGFR INHIBITORS BLUEPRINT MEDICINES CORPORATION (US) 2022-12-29 WO claimed
US-20220396576-A1 PROCESS FOR PREPARING AN ACTIVIN RECEPTOR-LIKE KINASE INHIBITOR BLUEPRINT MEDICINES CORPORATION 2022-12-15 US claimed
EP-4038071-A1 PROCESS FOR PREPARING AN ACTIVIN RECEPTOR-LIKE KINASE INHIBITOR Blueprint Medicines Corporation (US) 2022-08-10 EP claimed
WO-2022136049-A2 ORGANOMETALLIC COMPOUNDS UMICORE AG & CO. KG (DE) 2022-06-30 WO claimed
CN-114502558-A Method for preparing activin receptor-like kinase inhibitors 缆图药品公司 2022-05-13 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062374-A1 PROCESS FOR THE PREPARATION OF A BENZENE DERIVATIVE BRDT, CYP3A7, TP53 MAPT 4692/4885NSD2 2996/4885ALDH1A1 962/4885
US-20250388564-A1 METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS MUSK, SMN1; SMN2, PAX3 MAPT 4814/4885NSD2 2958/4885ALDH1A1 469/4885
US-20240300922-A1 PROCESS FOR PREPARING EGFR INHIBITORS EGFR, ERBB2, ERBB4 MAPT 2551/4885NSD2 4179/4885ALDH1A1 2197/4885
US-20220396576-A1 PROCESS FOR PREPARING AN ACTIVIN RECEPTOR-LIKE KINASE INHIBITOR ACVR1, ACVRL1, BMP2K MAPT 4632/4885NSD2 4360/4885ALDH1A1 3481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.