Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | TP53 | P04637 | 4/20 | 1.00 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | MMP1 | P03956 | 5/20 | 0.79 |
| ▸ | MMP2 | P08253 | 5/20 | 0.79 |
| ▸ | MMP9 | P14780 | 5/20 | 0.79 |
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296015 | 1.00 | KMT2A (1.00) | KMT2AMAPTMEN1TP53TRPV1 | |
| SCHEMBL1595342 | 1.00 | KMT2A (1.00) | KMT2AMAPTMEN1TP53TRPV1 | |
| SCHEMBL247433 | 0.88 | MMP1 (1.00) | KMT2AMAPTMEN1TP53TRPV1 | |
| SCHEMBL30080242 | 0.88 | MMP1 (1.00) | KMT2AMAPTMEN1TP53TRPV1 | |
| SCHEMBL247434 | 0.88 | MMP1 (1.00) | KMT2AMAPTMEN1TP53TRPV1 | |
| SCHEMBL247432 | 0.88 | MMP1 (1.00) | KMT2AMAPTMEN1TP53TRPV1 | |
| SCHEMBL5793760 | 0.87 | ALDH1A1 (0.77) | KMT2AMAPTMEN1TP53TRPV1 | |
| SCHEMBL13675628 | 0.85 | TRPV1 (1.00) | KMT2AMAPTMEN1TP53TRPV1 | |
| SCHEMBL21625686 | 0.84 | MAPT (1.00) | KMT2AMAPTMEN1TP53TRPV1 | |
| SCHEMBL26458454 | 0.83 | MMP1 (0.78) | KMT2AMAPTMEN1TP53TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250186375-A1 | TREATMENT FOR HOT FLUSHES | DIGNITY HEALTH | 2025-06-12 | — | — | US | claimed |
| CN-119955884-A | Oat polypeptide extracted by directional enzyme digestion and method and application thereof | 杭州恩和生物科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119639852-A | Preparation process and application of small fruit coffee grounds derived polypeptides | 杭州恩和生物科技有限公司 | 2025-03-18 | — | — | CN | claimed |
| US-20250017954-A1 | Formulations and Methods for Treating Symptoms of Menopause | Kindra Corporation (US) | 2025-01-16 | — | — | US | claimed |
| US-12186314-B2 | Compositions and methods for treatment, amelioration, and prevention of anesthesia-induced hypothermia | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2025-01-07 | — | — | US | claimed |
| US-20240408041-A1 | COMPOSITIONS AND METHODS FOR TREATING CANNABINOID HYPEREMESIS SYNDROME | HABBOUSHE JOSEPH (US) | 2024-12-12 | — | — | US | claimed |
| EP-4433045-A2 | FORMULATIONS AND METHODS FOR TREATING SYMPTOMS OF MENOPAUSE | KINDRA CORPORATION (US) | 2024-09-25 | — | — | EP | claimed |
| CN-118510501-A | Formulations and methods for treating climacteric symptoms | 金卓拉公司 | 2024-08-16 | — | — | CN | claimed |
| US-12036218-B2 | Modulators of airway basal cells for the treatment or prevention of lung diseases | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) | 2024-07-16 | — | — | US | claimed |
| CN-116966171-A | Application of TRPV1 antagonist in preparation of breast cancer treatment drug | 南通大学 | 2023-10-31 | — | — | CN | claimed |
| WO-2023091628-A2 | FORMULATIONS AND METHODS FOR TREATING SYMPTOMS OF MENOPAUSE | PG13 LAUNCHPAD ALPHA, INC. DBA KINDRA (US) | 2023-05-25 | — | — | WO | claimed |
| EP-3393462-B1 | COMPOSITIONS AND METHODS FOR TREATMENT, AMELIORATION, AND PREVENTION OF ANESTHESIA-INDUCED HYPOTHERMIA | UNIV ARIZONA (US) | 2023-02-01 | — | — | EP | claimed |
| CN-114601912-A | Itch-caused polypeptide caused by tick and mosquito bites and itch-resisting application thereof | 武汉大学 | 2022-06-10 | — | — | CN | claimed |
| EP-4048809-B1 | SYSTEMS AND METHODS FOR PREDICTING THERAPEUTIC SENSITIVITY | TEMPUS AI INC (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2026087527-A1 | NOVEL TRPM4 ANTAGONISTS AND MEDICAL USE THEREOF | Universitätsklinikum Hamburg-Eppendorf (DE) | 2026-04-30 | — | — | WO | disclosed |
| EP-4733298-A1 | NOVEL TRPM4 ANTAGONISTS AND MEDICAL USE THEREOF | Universitätsklinikum Hamburg-Eppendorf (DE) | 2026-04-29 | — | — | EP | disclosed |
| US-20220162198-A1 | COMPOSITIONS AND METHODS FOR INCREASING MUSCLE MASS AND OXIDATIVE METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-26 | — | — | US | disclosed |
| WO-2022082050-A1 | COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF ITCH | DUKE UNIVERSITY (US) | 2022-04-21 | — | — | WO | disclosed |
| EP-3952849-A2 | COMPOSITIONS AND METHODS FOR INCREASING MUSCLE MASS AND OXIDATIVE METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-02-16 | — | — | EP | disclosed |
| US-11241442-B2 | Methods of use for TRP channel antagonist-based combination cancer therapies | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250186375-A1 | TREATMENT FOR HOT FLUSHES | TRPV1, TRPA1, TRPV2 | KMT2A 1037/4885MAPT 2249/4885MEN1 3884/4885 |
| US-20220162198-A1 | COMPOSITIONS AND METHODS FOR INCREASING MUSCLE MASS AND OXIDATIVE METABOLISM | CPT1B, GYS1, PYGM | KMT2A 3365/4885MAPT 4034/4885MEN1 4764/4885 |
| US-20240408041-A1 | COMPOSITIONS AND METHODS FOR TREATING CANNABINOID HYPEREMESIS SYNDROME | CNR2, TRPV1, CNR1 | KMT2A 2248/4885MAPT 3487/4885MEN1 2930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.