SCHEMBL29394869

SCHEMBL29394869

CSCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PDCD1LG2 Q9BQ51 1/20 0.42
▸ CD274 Q9NZQ7 1/20 0.42
▸ CRHR1 P34998 1/20 0.40
▸ CRHR2 Q13324 1/20 0.40
▸ ITGB3 P05106 1/20 0.40
▸ ITGAV P06756 1/20 0.40
▸ CALCR P30988 3/20 0.40
▸ BACE1 P56817 7/20 0.39
▸ GRPR P30550 1/20 0.38
▸ KEAP1 Q14145 1/20 0.37
▸ CTSD P07339 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29805149 0.87 CALCR (0.48) CRHR1CRHR2CALCRBACE1GRPR
SCHEMBL29805325 0.85 BACE1 (0.44) BACE1CTSD
SCHEMBL29589213 0.84 FNTA (0.42) GRPR
SCHEMBL31257073 0.84 MAGI3 (0.44) BACE1GRPRCTSD
SCHEMBL31307253 0.83 CRHR1 (0.49) CRHR1CRHR2CALCRBACE1KEAP1
SCHEMBL29373353 0.83 CRHR1 (0.42) CRHR1CRHR2CALCRBACE1CTSD
SCHEMBL31257072 0.82 MAGI3 (0.48) CRHR1CRHR2CALCRBACE1
SCHEMBL31257048 0.82 CTSL (0.45) ITGB3ITGAVGRPRKEAP1
SCHEMBL30390358 0.81 CD274 (0.41) PDCD1LG2CD274BACE1CTSD
SCHEMBL31412207 0.81 OPRD1 (0.46) BACE1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629409-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2026-05-19 — — US disclosed
US-20240226261-A9 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-07-11 — — US disclosed
US-20240148849-A1 IMMUNOGENIC COMPOSITION, USE AND METHODS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-05-09 — — US disclosed
US-20240131136-A1 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-04-25 — — US disclosed
EP-4294433-A1 IMMUNOGENIC COMPOSITION, USE AND METHODS GlaxoSmithKline Biologicals SA (BE) 2023-12-27 — — EP disclosed
US-11844828-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-12-19 — — US disclosed
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-08-10 — — US disclosed
US-20230066762-A1 IMMUNOGENIC COMPOSITION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-02 — — US disclosed
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-09-15 — — US disclosed
WO-2022175423-A1 IMMUNOGENIC COMPOSITION, USE AND METHODS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-08-25 — — WO disclosed
US-20220221455-A1 ANTIGEN BINDING PROTEINS AND ASSAYS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-07-14 — — US disclosed
CN-114667158-A Immunogenic compositions 葛兰素史克生物有限公司 2022-06-24 — — CN disclosed
EP-4009951-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GlaxoSmithKline Biologicals S.A. (BE) 2022-06-15 — — EP disclosed
EP-4010014-A1 IMMUNOGENIC COMPOSITION GlaxoSmithKline Biologicals S.A. (BE) 2022-06-15 — — EP disclosed
US-20220152182-A1 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-05-19 — — US disclosed
CN-114245746-A Methods for preparing compositions comprising protein D polypeptides 葛兰素史克生物有限公司 2022-03-25 — — CN disclosed
US-11266731-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-03-08 — — US disclosed
EP-3956666-A1 ANTIGEN BINDING PROTEINS AND ASSAYS GlaxoSmithKline Biologicals S.A. (BE) 2022-02-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 PDCD1LG2 1153/4885CD274 2578/4885CRHR1 1654/4885
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 PDCD1LG2 1153/4885CD274 2578/4885CRHR1 1654/4885
US-12629409-B2 Vaccine MRPL21, STT3B, CD47 PDCD1LG2 1212/4885CD274 932/4885CRHR1 4225/4885
US-20230066762-A1 IMMUNOGENIC COMPOSITION CXCL10, CCL2, CCL11 PDCD1LG2 1049/4885CD274 1027/4885CRHR1 1576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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