Deldeprevir

Deldeprevir

SCHEMBL29399555

COc1ccc2c(O[C@@H]3C[C@H]4C(=O)N[C@]5(C(=O)NS(=O)(=O)C6CC6)C[C@H]5/C=C\CCCCC[C@H](CC(=O)N5CCCC(F)(F)C5)C(=O)N4C3)cc(-c3nc(C(C)C)cs3)nc2c1C

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CTSS P25774 1/20 0.67
▸ ADRB3 P13945 1/20 0.51
▸ ADRA2B P18089 1/20 0.51
▸ ADRA2C P18825 1/20 0.51
▸ CTSB P07858 1/20 0.43
▸ CYP3A4 P08684 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deldeprevir SCHEMBL16020696 1.00 CTSS (0.67) CTSSADRB3ADRA2BADRA2CCTSB
Deldeprevir SCHEMBL13291708 1.00 CTSS (0.67) CTSSADRB3ADRA2BADRA2CCTSB
Deldeprevir SCHEMBL16020697 1.00 CTSS (0.67) CTSSADRB3ADRA2BADRA2CCTSB
SCHEMBL25524203 0.96 CTSS (0.60) CTSSADRB3ADRA2BADRA2CCTSB
SCHEMBL16927407 0.95 CTSS (0.72) CTSSADRB3ADRA2BADRA2CCTSB
SCHEMBL13291725 0.95 CTSS (0.72) CTSSADRB3ADRA2BADRA2CCTSB
SCHEMBL16927409 0.95 CTSS (0.72) CTSSADRB3ADRA2BADRA2CCTSB
SCHEMBL16927450 0.94 CTSS (0.68) CTSSADRB3ADRA2BADRA2CCTSB
SCHEMBL13291731 0.94 CTSS (0.68) CTSSADRB3ADRA2BADRA2CCTSB
SCHEMBL16927447 0.94 CTSS (0.68) CTSSADRB3ADRA2BADRA2CCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4094767-B1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-20 — — EP disclosed
EP-3448392-B1 ALKYNE CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-13 — — EP disclosed
US-20260124226-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-07 — — US disclosed
US-20260102422-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-04-16 — — US disclosed
US-20260091050-A1 ADVANTAGEOUS ANTI-HCV COMBINATION THERAPY Atea Pharmaceuticals, Inc. (US) 2026-04-02 — — US disclosed
EP-4346772-B1 PHOSPHOLIPID FORMULATIONS OF 1'-CYANO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS GILEAD SCIENCES INC (US) 2026-04-01 — — EP disclosed
EP-4714452-A1 METHODS FOR TREATING SARS COV-2 INFECTIONS Gilead Sciences, Inc. (US) 2026-03-25 — — EP disclosed
EP-4132651-B1 INHALATION FORMULATIONS OF 1'-CYANO SUBSTITUTED CARBANUCLEOSIDE ANALOGS GILEAD SCIENCES INC (US) 2026-03-18 — — EP disclosed
EP-4705284-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO Emory University (US) 2026-03-11 — — EP disclosed
US-12565665-B2 Compositions and methods for controlled mRNA translation and stability TRUSTEES OF BOSTON UNIVERSITY (US) 2026-03-03 — — US disclosed
US-20220143052-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-05-12 — — US disclosed
US-11318119-B2 HIV protease inhibitors GILEAD SCIENCES, INC. (US) 2022-05-03 — — US disclosed
EP-3043803-B1 NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND THEIR USES UNIV EMORY (US) 2022-04-27 — — EP disclosed
WO-2022081973-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2022-04-21 — — WO disclosed
US-20220098246-A1 CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION TRUSTEES OF BOSTON UNIVERSITY (US) 2022-03-31 — — US disclosed
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-03-17 — — US disclosed
US-20220072021-A1 COMBINATION FORMULATION OF TWO ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2022-03-10 — — US disclosed
US-20220073473-A1 TOLL LIKE RECEPTOR MODULATOR COMPOUNDS GILEAD SCIENCES, INC. 2022-03-10 — — US disclosed
WO-2022046631-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2022-03-03 — — WO disclosed
EP-3955921-A1 2-IMINO-5-OXO-IMIDAZOLIDINE INHIBITORS OF HIV PROTEASE GILEAD SCIENCES, INC. (US) 2022-02-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220143052-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 CTSS 1005/4885ADRB3 3789/4885ADRA2B 4205/4885
US-20220073473-A1 TOLL LIKE RECEPTOR MODULATOR COMPOUNDS TLR8, TLR3, TLR6 CTSS 3714/4885ADRB3 660/4885ADRA2B 864/4885
US-20260102422-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO SARS1, ITK, SLC43A1 CTSS 2914/4885ADRB3 1888/4885ADRA2B 3125/4885
US-12565665-B2 Compositions and methods for controlled mRNA translation and stability ADAR, ADA, NSUN2 CTSS 4768/4885ADRB3 3872/4885ADRA2B 3039/4885
US-11318119-B2 HIV protease inhibitors ACE, PRSS1, TMPRSS2 CTSS 12/4885ADRB3 3983/4885ADRA2B 4619/4885
US-20220098246-A1 CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION HAVCR2, CPB1, CTRL CTSS 53/4885ADRB3 3737/4885ADRA2B 3371/4885
US-20260124226-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO NSUN2, SARS1, SNRPE CTSS 3269/4885ADRB3 1698/4885ADRA2B 2945/4885
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 CTSS 951/4885ADRB3 3857/4885ADRA2B 4281/4885
US-20220072021-A1 COMBINATION FORMULATION OF TWO ANTIVIRAL COMPOUNDS EIF2AK2, SARS1, ZC3HAV1 CTSS 103/4885ADRB3 3055/4885ADRA2B 2858/4885
US-20260091050-A1 ADVANTAGEOUS ANTI-HCV COMBINATION THERAPY SLC10A1, SLC10A2, STAT3 CTSS 846/4885ADRB3 3229/4885ADRA2B 2298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback