Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124466 | 0.97 | NPSR1 (0.69) | NPSR1L3MBTL1LMNAALDH1A1CA2 | |
| SCHEMBL124993 | 0.97 | NPSR1 (0.69) | NPSR1L3MBTL1LMNAALDH1A1CA2 | |
| SCHEMBL124202 | 0.95 | NPSR1 (0.68) | NPSR1L3MBTL1LMNAALDH1A1CA2 | |
| SCHEMBL124204 | 0.95 | NPSR1 (0.68) | NPSR1L3MBTL1LMNAALDH1A1CA2 | |
| SCHEMBL5148115 | 0.90 | L3MBTL1 (0.59) | NPSR1L3MBTL1LMNAALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL2805432 | 0.85 | NPSR1 (0.71) | NPSR1L3MBTL1LMNAALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL29676296 | 0.84 | NPSR1 (0.69) | NPSR1L3MBTL1LMNAALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6682577 | 0.84 | NPSR1 (0.69) | NPSR1L3MBTL1LMNAALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6682576 | 0.84 | NPSR1 (0.69) | NPSR1L3MBTL1LMNAALDH1A1CYP2D6 | |
| SCHEMBL125500 | 0.83 | NPSR1 (0.73) | NPSR1L3MBTL1LMNAALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4744901-A1 | ON-PRESS DEVELOPMENT TYPE PLANOGRAPHIC PRINTING PLATE ORIGINAL PLATE, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, PLANOGRAPHIC PRINTING METHOD, AND COMPOUND | FUJIFILM Corporation (JP) | 2026-05-20 | — | — | EP | disclosed |
| US-20260131567-A1 | ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, LITHOGRAPHIC PRINTING METHOD, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2026-05-14 | — | — | US | disclosed |
| US-20260084408-A1 | POSITIVE TONE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2026-03-26 | — | — | US | disclosed |
| EP-4714657-A1 | POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM Corporation (JP) | 2026-03-25 | — | — | EP | disclosed |
| WO-2025013910-A1 | ON-PRESS DEVELOPMENT TYPE PLANOGRAPHIC PRINTING PLATE ORIGINAL PLATE, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, PLANOGRAPHIC PRINTING METHOD, AND COMPOUND | 富士フイルム株式会社 | 2025-01-16 | — | — | WO | disclosed |
| US-11835503-B2 | TMA-formation inhibitor treatment for elevated TMA-containing compound diseases | THE CLEVELAND CLINIC FOUNDATION (US) | 2023-12-05 | — | — | US | disclosed |
| CN-112714612-B | Compositions comprising PVA and certain herbicides with improved properties | 拜耳公司 | 2023-03-28 | — | — | CN | disclosed |
| US-20220254275-A1 | SYSTEM AND A METHOD FOR PROVIDING POSITIVE REINFORCEMENT ON APPROPRIATE FOOD ITEMS | VENUGOPAL KRISHNA SARATHY (US) | 2022-08-11 | — | — | US | disclosed |
| US-20220065829-A1 | TRIMETHYLAMINE-CONTAINING COMPOUNDS FOR DIAGNOSIS AND PREDICTION OF DISEASE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260131567-A1 | ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, LITHOGRAPHIC PRINTING METHOD, AND COMPOUND | LEF1, LARP1, RUVBL1 | ACHE 4859/4885NPSR1 3527/4885L3MBTL1 151/4885 |
| US-20260084408-A1 | POSITIVE TONE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | SUN2, LEF1, LCP1 | ACHE 4487/4885NPSR1 3795/4885L3MBTL1 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.