SCHEMBL29401751

SCHEMBL29401751

O=C(N[C@H](CCc1ccccc1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.57
TP53 P04637 3/20 0.57
MDM2 Q00987 6/20 0.53
CASP3 P42574 2/20 0.52
TLR2 O60603 2/20 0.52
TNF P01375 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30854556 1.00 MDM4 (0.57) MDM4TP53MDM2CASP3TLR2
SCHEMBL29401188 1.00 MDM4 (0.57) MDM4TP53MDM2CASP3TLR2
SCHEMBL119488 1.00 MDM4 (0.57) MDM4TP53MDM2CASP3TLR2
SCHEMBL2307942 1.00 MDM4 (0.57) MDM4TP53MDM2CASP3TLR2
SCHEMBL800091 1.00 MDM4 (0.57) MDM4TP53MDM2CASP3TLR2
SCHEMBL29516375 0.93 MDM4 (0.53) MDM4TP53MDM2CASP3TLR2
SCHEMBL430008 0.93 MDM2 (0.56) MDM4TP53MDM2CASP3TLR2
SCHEMBL30861860 0.93 MDM2 (0.56) MDM4TP53MDM2CASP3TLR2
SCHEMBL3732565 0.93 MDM2 (0.56) MDM4TP53MDM2CASP3TLR2
SCHEMBL3733904 0.93 MDM2 (0.56) MDM4TP53MDM2CASP3TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US disclosed
EP-4732286-A2 COMPOSITIONS AND METHODS FOR ENCRYPTING, STORING, AND DECRYPTING INFORMATION IN OLIGOMERS Board of Regents, The University of Texas System (US) 2026-04-29 EP disclosed
EP-3455234-B1 SECO MACROLIDE COMPOUNDS SELVITA D O O (HR) 2026-04-01 EP disclosed
US-12565518-B2 Hybrid cyclic libraries and screens thereof THE JOHNS HOPKINS UNIVERSITY (US) 2026-03-03 US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 EP disclosed
WO-2025094930-A1 CYANINE COMPOUND AND USE THEREOF 学校法人東京薬科大学 2025-05-08 WO disclosed
WO-2025058677-A2 COMPOSITIONS AND METHODS FOR ENCRYPTING, STORING, AND DECRYPTING INFORMATION IN OLIGOMERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-03-20 WO disclosed
US-12157778-B2 Peptides for activation of cell signaling in osteoprogenitor cells THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-03 US disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20230096766-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-03-30 US disclosed
US-20230041996-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOUND AND APPLICATION THEREOF BEIJING TUO JIE BIOPHARMACEUTICAL CO. LTD. (CN) 2023-02-09 US disclosed
US-11512096-B2 Seco macrolide compounds SELVITA D.O.O. (HR) 2022-11-29 US disclosed
EP-4091623-A1 CALCIUM-SENSING RECEPTOR AGONIST COMPOUND AND APPLICATION THEREOF Beijing Tuo Jie Biopharmaceutical Co. Ltd. (CN) 2022-11-23 EP disclosed
US-20220289802-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME CORNELL UNIVERSITY 2022-09-15 US disclosed
US-11440938-B2 Stabilized minimal coiled-coil mimetics NEW YORK UNIVERSITY (US) 2022-09-13 US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
EP-3287458-B1 HYBRID CYCLIC LIBRARIES AND SCREENING THEREOF UNIV JOHNS HOPKINS (US) 2022-07-13 EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565518-B2 Hybrid cyclic libraries and screens thereof NOLC1, BCL6, CHP1 MDM4 2638/4885TP53 302/4885MDM2 1689/4885
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH MDM4 2743/4885TP53 3446/4885MDM2 777/4885
US-11440938-B2 Stabilized minimal coiled-coil mimetics COIL, CALCOCO2, SMC2 MDM4 256/4885TP53 657/4885MDM2 420/4885
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN GLP1R, ALB, GIPR MDM4 4874/4885TP53 2182/4885MDM2 1864/4885
US-11512096-B2 Seco macrolide compounds SEC61B, SEC16A, SEC61A1 MDM4 3271/4885TP53 4852/4885MDM2 4514/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 MDM4 2407/4885TP53 2772/4885MDM2 908/4885
US-20220289802-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH MDM4 2743/4885TP53 3446/4885MDM2 777/4885
US-12157778-B2 Peptides for activation of cell signaling in osteoprogenitor cells ITGB4, ITGA4, ITGB1 MDM4 2824/4885TP53 3140/4885MDM2 3897/4885
US-20230096766-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF VIP, DNPEP, HM13 MDM4 3098/4885TP53 3050/4885MDM2 3655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.