SCHEMBL29417385

SCHEMBL29417385

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PTH1R Q03431 2/20 0.54
▸ TFPI P10646 1/20 0.54
▸ VIPR1 P32241 2/20 0.53
▸ KISS1R Q969F8 2/20 0.52
▸ VIPR2 P41587 2/20 0.52
▸ ECE1 P42892 1/20 0.51
▸ GLP1R P43220 1/20 0.51
▸ MUS81 Q96NY9 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30198769 0.93 TFPI (0.65) PTH1RTFPIVIPR1VIPR2
SCHEMBL30571155 0.91 BACE1 (0.54) PTH1RVIPR1KISS1RVIPR2
SCHEMBL20764456 0.90 TFPI (0.57) TFPI
SCHEMBL30974237 0.90 TFPI (0.58) PTH1RTFPIVIPR1VIPR2ECE1
SCHEMBL30974318 0.90 TFPI (0.58) PTH1RTFPIVIPR1VIPR2ECE1
SCHEMBL30974343 0.90 TFPI (0.58) PTH1RTFPIVIPR1VIPR2ECE1
SCHEMBL30512795 0.89 KISS1R (0.62) PTH1RTFPIVIPR1KISS1RVIPR2
SCHEMBL30974472 0.89 TFPI (0.58) PTH1RTFPIVIPR1KISS1RVIPR2
SCHEMBL29679607 0.89 TFPI (0.56) TFPIVIPR1KISS1RVIPR2ECE1
SCHEMBL30974327 0.89 TFPI (0.53) PTH1RTFPIVIPR1VIPR2ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005750-A Application of bombyx mori neuropeptide BommoOKA _type4 in preparation of anti-melanoma medicine 广西壮族自治区蚕业技术推广站(广西壮族自治区蚕种质量检验检疫站、广西壮族自治区蚕业科学研究院) 2026-05-12 — — CN disclosed
US-12613247-B2 Labelling method to distinguish isobaric amino acids and amino acid combinations RAPID NOVOR INC. (CA) 2026-04-28 — — US disclosed
CN-121248746-A Brown planthopper myophilic neuropeptide orcokinin-A and application thereof 扬州大学 2026-01-02 — — CN disclosed
CN-121248746-A Brown planthopper myophilic neuropeptide orcokinin-A and application thereof 扬州大学 2026-01-02 — — CN disclosed
US-20250388544-A1 HETEROAROMATIC INHIBITORS OF ASTACIN PROTEINASES VIVORYON THERAPEUTICS N.V. (DE) 2025-12-25 — — US disclosed
US-12378186-B2 Inhibitors of meprin α and β VIVORYON THERAPEUTICS N.V. (DE) 2025-08-05 — — US disclosed
EP-3750878-B1 HETEROAROMATIC INHIBITORS OF ASTACIN PROTEINASES VIVORYON THERAPEUTICS N V (DE) 2025-05-14 — — EP disclosed
EP-3967679-B1 NOVEL INHIBITORS OF MEPRIN ALPHA AND BETA VIVORYON THERAPEUTICS AG (DE) 2025-02-19 — — EP disclosed
CN-114507175-B Novel inhibitors of hypnotins alpha and beta 维沃里翁治疗股份有限公司 2024-10-01 — — CN disclosed
EP-3899532-B1 A LABELLING METHOD TO DISTINGUISH ISOBARIC AMINO ACIDS AND AMINO ACID COMBINATIONS RAPID NOVOR INC (CA) 2024-02-14 — — EP disclosed
US-20230122243-A1 Heteroaromatic inhibitors of astacin proteinases VIVORYON THERAPEUTICS N.V. (DE) 2023-04-20 — — US disclosed
CN-114585608-A Heteroaromatic inhibitors of astacin protease 维沃永治疗公众有限公司 2022-06-03 — — CN disclosed
CN-114507175-A Novel inhibitors of hypnotic proteins alpha and beta 维沃里翁治疗股份有限公司 2022-05-17 — — CN disclosed
EP-3986868-A1 HETEROAROMATIC INHIBITORS OF ASTACIN PROTEINASES Vivoryon Therapeutics N.V. (DE) 2022-04-27 — — EP disclosed
EP-3967679-A1 NOVEL INHIBITORS OF MEPRIN ALPHA AND BETA Vivoryon Therapeutics AG (DE) 2022-03-16 — — EP disclosed
CN-109195947-B Novel inhibitors of hypnotic proteins alpha and beta 维沃里翁治疗股份有限公司 2022-03-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230122243-A1 Heteroaromatic inhibitors of astacin proteinases BMP1, DPEP1, MEP1A PTH1R 709/4885TFPI 799/4885VIPR1 2017/4885
US-20250388544-A1 HETEROAROMATIC INHIBITORS OF ASTACIN PROTEINASES BMP1, BMPR1A, BMPR1B PTH1R 1055/4885TFPI 1496/4885VIPR1 1801/4885
US-12613247-B2 Labelling method to distinguish isobaric amino acids and amino acid combinations DNPEP, ASNS, ANPEP PTH1R 1634/4885TFPI 2335/4885VIPR1 705/4885
US-12378186-B2 Inhibitors of meprin α and β MEP1A, MEP1B, CAPRIN1 PTH1R 2407/4885TFPI 236/4885VIPR1 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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