Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 3/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29575698 | 1.00 | FOLH1 (0.39) | FOLH1NAALAD2ALDH1A1MAPTENPEP | |
| SCHEMBL29429643 | 0.87 | GNPAT (0.43) | FOLH1NAALAD2ENPEPNOD1 | |
| SCHEMBL930374 | 0.83 | ACE (0.51) | FOLH1MAPTENPEPMMEACE | |
| SCHEMBL29546590 | 0.83 | DPP4 (0.53) | FOLH1NAALAD2 | |
| SCHEMBL30193478 | 0.83 | SLC7A5 (0.47) | FOLH1ALDH1A1MAPTLAP3MME | |
| SCHEMBL29429648 | 0.82 | GNPAT (0.49) | FOLH1NAALAD2ENPEPNOD1 | |
| SCHEMBL29429649 | 0.82 | GNPAT (0.49) | FOLH1NAALAD2ENPEPNOD1 | |
| SCHEMBL29429642 | 0.81 | GNPAT (0.44) | FOLH1NAALAD2ENPEPNOD1 | |
| SCHEMBL29429644 | 0.81 | GNPAT (0.44) | FOLH1NAALAD2ENPEPNOD1 | |
| Leu-Leu SCHEMBL235250 | 0.80 | ALDH1A1 (0.60) | FOLH1ALDH1A1MAPTLAP3MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12397060-B2 | pHLIP®-mediated intracellular delivery of immuno-stimulatory compounds | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2025-08-26 | — | — | US | disclosed |
| US-12290575-B2 | Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2025-05-06 | — | — | US | disclosed |
| US-20240342296-A1 | pH LOW INSERTION PEPTIDE TARGETED DELIVERY OF POTENT CYTOTOXIC COMPOUNDS | YALE UNIVERSITY | 2024-10-17 | — | — | US | disclosed |
| US-12029793-B2 | pH low insertion peptide targeted delivery of potent cytotoxic compounds | YALE UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| US-20240148911-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH-TRIGGERED POLYPEPTIDE | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-05-09 | — | — | US | disclosed |
| US-20240075170-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH-TRIGGERED POLYPEPTIDE | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-03-07 | — | — | US | disclosed |
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-02-08 | — | — | US | disclosed |
| US-20230372551-A1 | RADIOLABELED LIGANDS FOR TARGETED PET/SPECT IMAGING AND METHODS OF THEIR USE | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2023-11-23 | — | — | US | disclosed |
| US-11779662-B2 | Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2023-10-10 | — | — | US | disclosed |
| US-11738096-B2 | Method of detecting diseased or damaged tissue with a pH-triggered polypeptide fluorophore composition | YALE UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| US-20220088208-A1 | PHLIP®-MEDIATED INTRACELLULAR DELIVERY OF IMMUNO-STIMULATORY COMPOUNDS | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2022-03-24 | — | — | US | disclosed |
| US-11267853-B2 | Carbohydrate tethering at cell surfaces to induce immune response | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2022-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240342296-A1 | pH LOW INSERTION PEPTIDE TARGETED DELIVERY OF POTENT CYTOTOXIC COMPOUNDS | PMAIP1, SCAMP2, CHERP | FOLH1 1300/4885NAALAD2 1298/4885ALDH1A1 4856/4885 |
| US-11738096-B2 | Method of detecting diseased or damaged tissue with a pH-triggered polypeptide fluorophore composition | VIP, FUCA1, FGB | FOLH1 26/4885NAALAD2 227/4885ALDH1A1 2938/4885 |
| US-11267853-B2 | Carbohydrate tethering at cell surfaces to induce immune response | CD4, CD14, CD69 | FOLH1 775/4885NAALAD2 796/4885ALDH1A1 4858/4885 |
| US-20220088208-A1 | PHLIP®-MEDIATED INTRACELLULAR DELIVERY OF IMMUNO-STIMULATORY COMPOUNDS | STING1, MAVS, IRF3 | FOLH1 1135/4885NAALAD2 2632/4885ALDH1A1 4863/4885 |
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | LIPA, PHOSPHO1, NGLY1 | FOLH1 43/4885NAALAD2 134/4885ALDH1A1 4722/4885 |
| US-20240075170-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH-TRIGGERED POLYPEPTIDE | NPPA, LNPEP, VIP | FOLH1 10/4885NAALAD2 59/4885ALDH1A1 2449/4885 |
| US-20240148911-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH-TRIGGERED POLYPEPTIDE | NPPA, LNPEP, VIP | FOLH1 10/4885NAALAD2 59/4885ALDH1A1 2449/4885 |
| US-12397060-B2 | pHLIP®-mediated intracellular delivery of immuno-stimulatory compounds | STING1, MAVS, IRF3 | FOLH1 1135/4885NAALAD2 2632/4885ALDH1A1 4863/4885 |
| US-12290575-B2 | Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide | NPPA, LNPEP, VIP | FOLH1 10/4885NAALAD2 59/4885ALDH1A1 2449/4885 |
| US-12029793-B2 | pH low insertion peptide targeted delivery of potent cytotoxic compounds | SLC7A1, SLC47A1, VIP | FOLH1 501/4885NAALAD2 840/4885ALDH1A1 4770/4885 |
| US-20230372551-A1 | RADIOLABELED LIGANDS FOR TARGETED PET/SPECT IMAGING AND METHODS OF THEIR USE | MPI, FOLH1, GRPR | FOLH1 2/4885NAALAD2 249/4885ALDH1A1 4696/4885 |
| US-11779662-B2 | Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide | NPPA, LNPEP, VIP | FOLH1 10/4885NAALAD2 59/4885ALDH1A1 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.