Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Asparagine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 known ✓ | P39086 | 7/20 | 0.52 |
| ▸ | GRIK2 known ✓ | Q13002 | 4/20 | 0.52 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.48 |
| ▸ | GRIA4 known ✓ | P48058 | 4/20 | 0.45 |
| ▸ | GRIK3 known ✓ | Q13003 | 4/20 | 0.45 |
| ▸ | GRIK5 known ✓ | Q16478 | 4/20 | 0.45 |
| ▸ | GRIA2 known ✓ | P42262 | 3/20 | 0.44 |
| ▸ | GRIA1 known ✓ | P42261 | 2/20 | 0.44 |
| ▸ | GRIA3 known ✓ | P42263 | 1/20 | 0.44 |
| ▸ | GRIN2A known ✓ | Q12879 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.48 |
| ▸ | GGT1 | P19440 | 4/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Asparagine SCHEMBL28655930 | 1.00 | ALOX15 (0.54) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL656714 | 1.00 | ALOX15 (0.54) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL28655929 | 1.00 | ALOX15 (0.54) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL8103410 | 1.00 | ALOX15 (0.54) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL50255 | 1.00 | ALOX15 (0.54) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL656713 | 1.00 | ALOX15 (0.54) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL50254 | 1.00 | ALOX15 (0.54) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL28196111 | 0.97 | ALOX15 (0.52) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL31634581 | 0.97 | ALOX15 (0.52) | ALOX15BLMPMP22KMT2AGRIK1 | |
| Asparagine SCHEMBL150535 | 0.97 | ALOX15 (0.56) | ALOX15BLMPMP22KMT2AGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017496-B1 | FORMULATIONS FOR USE IN THE PREVENTION AND/OR TREATMENT OF PERIPHERAL NEUROPATHY AND ITS ASSOCIATED DISEASES | LOH YIN SZE (SG) | 2026-01-07 | — | — | EP | claimed |
| EP-3911339-B1 | PLATELET RICH-FIBRIN DERIVED MESENCHYMAL STEM CELLS | T C ERCIYES UENIVERSITESI (TR) | 2025-01-08 | — | — | EP | claimed |
| WO-2023277639-A1 | MEDIUM FOR CULTURING NATURAL KILLER CELLS, AND METHOD FOR MASS-PROPAGATING NATURAL KILLER CELLS USING SAME | 엔케이젠 주식회사 | 2023-01-05 | — | — | WO | claimed |
| CN-112375733-B | Phytohemagglutinin capable of improving stem cell performance of mesenchymal stem cells and application of phytohemagglutinin in amplification culture of mesenchymal stem cells | 中国人民解放军陆军军医大学第一附属医院 | 2022-09-02 | — | — | CN | claimed |
| US-11345887-B2 | Composition for preserving cells, containing, as active ingredients, plant-derived recombinant human serum albumin and plant peptides | CEFO CO., LTD (KR) | 2022-05-31 | — | — | US | claimed |
| US-20260049281-A1 | Cell cultivation processes for preparing food products, products provided by said processes and a system for providing these processes | BTL HEALTHCARE TECHNOLOGIES AS (CZ) | 2026-02-19 | — | — | US | disclosed |
| US-20250368948-A1 | PRODUCT, SYSTEM AND METHOD OF CELL CULTIVATION | BTL Healthcare Technologies a,s. | 2025-12-04 | — | — | US | disclosed |
| US-20250270503-A1 | Product, system and method of cell cultivation | BTL HEALTHCARE TECHNOLOGIES A.S. | 2025-08-28 | — | — | US | disclosed |
| US-20250236833-A1 | Product, system and method of cell cultivation | BTL HEALTHCARE TECHNOLOGIES A.S. | 2025-07-24 | — | — | US | disclosed |
| US-20250234856-A1 | ADIPOSE TISSUE TRANSPORT PRESERVATION SOLUTION | WUXI CELLULAR BIOPHARMACEUTICAL GROUP LTD. (CN) | 2025-07-24 | — | — | US | disclosed |
| US-12291721-B2 | Activated lymphocytes comprising cytokine-induced killer cells and preparation method therefor | GREENCROSSCELL (KR) | 2025-05-06 | — | — | US | disclosed |
| US-20250122476-A1 | PET FOOD, METHODS AND DEVICES FOR PRODUCING PET FOOD | BTL HEALTHCARE TECHNOLOGIES A.S. | 2025-04-17 | — | — | US | disclosed |
| CN-112375733-B | Phytohemagglutinin capable of improving stem cell performance of mesenchymal stem cells and application of phytohemagglutinin in amplification culture of mesenchymal stem cells | 中国人民解放军陆军军医大学第一附属医院 | 2022-09-02 | — | — | CN | disclosed |
| CN-112300985-B | Proliferation culture medium and proliferation culture method for rapidly improving proliferation efficiency of mesenchymal stem cells of mammals | 中国人民解放军陆军军医大学第一附属医院 | 2022-07-01 | — | — | CN | disclosed |
| CN-114555786-A | Method for in vitro production of mammalian neurons | 波尔多大学 | 2022-05-27 | — | — | CN | disclosed |
| US-20220160763-A1 | ACTIVATED LYMPHOCYTES COMPRISING CYTOKINE-INDUCED KILLER CELLS AND PREPARATION METHOD THEREFOR | GREENCROSSCELL (KR) | 2022-05-26 | — | — | US | disclosed |
| US-20220135938-A1 | NUTRITION COMPOSITION | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2022-05-05 | — | — | US | disclosed |
| CN-108350480-B | Method for evaluating differentiation state of cell | 株式会社岛津制作所 | 2022-04-22 | — | — | CN | disclosed |
| US-11293008-B2 | Media for culturing epithelial cells | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-05 | — | — | US | disclosed |
| US-20220082564-A1 | MARKER FOR ASSESSING SENSITIVITY TO COMBINATION ANTICANCER DRUG | KEIO UNIVERSITY (JP) | 2022-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260049281-A1 | Cell cultivation processes for preparing food products, products provided by said processes and a system for providing these processes | HCLS1, FIP1L1, HRAS | GRIK1 4835/4885GRIK2 4766/4885PTGS1 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.