Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
| ▸ | PNP | P00491 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23734167 | 1.00 | POLA1 (0.54) | POLA1PNPLMNATP53HTT | |
| SCHEMBL22571146 | 1.00 | POLA1 (0.54) | POLA1PNPLMNATP53HTT | |
| SCHEMBL19662722 | 1.00 | POLA1 (0.54) | POLA1PNPLMNATP53HTT | |
| SCHEMBL17222408 | 0.89 | POLA1 (0.53) | POLA1PNPLMNATP53HTT | |
| SCHEMBL17222404 | 0.89 | POLA1 (0.53) | POLA1PNPLMNATP53HTT | |
| SCHEMBL5059377 | 0.88 | POLA1 (0.58) | POLA1PNPLMNATP53HTT | |
| SCHEMBL19662721 | 0.87 | POLB (0.47) | POLA1PNPLMNATP53HTT | |
| SCHEMBL26156310 | 0.86 | KDM4E (0.51) | POLA1PNPLMNATP53HTT | |
| SCHEMBL19662716 | 0.86 | POLB (0.46) | POLA1PNPLMNATP53HTT | |
| SCHEMBL20684464 | 0.85 | POLA1 (0.54) | POLA1PNPLMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181147-A | Preparation method of C4 '-trifluoromethylthio modified nucleoside and C4' -trifluoromethylthio modified nucleic acid | 南开大学 | 2022-10-14 | — | — | CN | claimed |
| CN-109863161-B | Labeled polynucleotides useful for nucleic acid sequencing | 豪夫迈·罗氏有限公司 | 2022-06-03 | — | — | CN | claimed |
| US-20260028368-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | INTEGRATED DNA TECH INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12502354-B2 | High density lipoprotein mimetic nanoparticles using lipid conjugated core scaffolds | NORTHWESTERN UNIVERSITY (US) | 2025-12-23 | — | — | US | disclosed |
| US-12459968-B2 | Oligonucleotide synthesis on solid support | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| CN-222961346-U | Oligonucleotide synthesizer | 北京铭毅智造科技有限公司 | 2025-06-10 | — | — | CN | disclosed |
| US-20240343752-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | UNIV BERN (CH) | 2024-10-17 | — | — | US | disclosed |
| US-20240264142-A1 | MOLECULAR DETECTION AND COUNTING USING NANOPORES | ROCHE SEQUENCING SOLUTIONS INC (US) | 2024-08-08 | — | — | US | disclosed |
| US-20240255495-A1 | COVALENT APTAMERS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2024-08-01 | — | — | US | disclosed |
| CN-115181147-B | Preparation method of C4 '-trifluoromethylthio modified nucleoside and C4' -trifluoromethylthio modified nucleic acid | 南开大学 | 2024-04-02 | — | — | CN | disclosed |
| US-11919922-B2 | Bicyclic nucleosides and oligomers prepared therefrom | UNIVERSITAT BERN (CH) | 2024-03-05 | — | — | US | disclosed |
| US-20230059186-A1 | METHODS AND COMPOSITIONS RELATED TO A HYBRID DNA REPAIR GLYCOSYLASE AND A THERMOSTABLE DNA LYASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2023-02-23 | — | — | US | disclosed |
| EP-4110789-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | Integrated Dna Technologies, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| WO-2022232195-A2 | COVALENT APTAMERS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-11-03 | — | — | WO | disclosed |
| CN-115181147-A | Preparation method of C4 '-trifluoromethylthio modified nucleoside and C4' -trifluoromethylthio modified nucleic acid | 南开大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-109863161-B | Labeled polynucleotides useful for nucleic acid sequencing | 豪夫迈·罗氏有限公司 | 2022-06-03 | — | — | CN | disclosed |
| US-20220151928-A1 | HIGH DENSITY LIPOPROTEIN MIMETIC NANOPARTICLES USING LIPID CONJUGATED CORE SCAFFOLDS | NORTHWESTERN UNIVERSITY (US) | 2022-05-19 | — | — | US | disclosed |
| WO-2022087452-A1 | HYDROPHOBIC DRUGS IN ORGANIC CORE HIGH DENSITY LIPOPROTEIN (HDL) NANOPARTICLES | NORTHWESTERN UNIVERSITY (US) | 2022-04-28 | — | — | WO | disclosed |
| US-20220089632-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | UNIV BERN (CH) | 2022-03-24 | — | — | US | disclosed |
| WO-2022041860-A1 | FUNCTIONALIZED SURFACE TREATMENT METHOD FOR USE IN HIGH-THROUGHPUT NUCLEIC ACID IN SITU SYNTHESIS BY 3D INKJET METHOD | 上海迪赢生物科技有限公司 | 2022-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089632-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | RRM2, PRPF31, PYGM | POLA1 89/4885PNP 8/4885LMNA 309/4885 |
| US-20240343752-A1 | NOVEL BICYCLIC NUCLEOSIDES AND OLIGOMERS PREPARED THEREFROM | RRM2, RRM2B, REV1 | POLA1 76/4885PNP 14/4885LMNA 305/4885 |
| US-20260028368-A1 | OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT | NSUN2, RNGTT, POLR2H | POLA1 17/4885PNP 202/4885LMNA 374/4885 |
| US-12459968-B2 | Oligonucleotide synthesis on solid support | RNGTT, SSU72, NSUN2 | POLA1 46/4885PNP 78/4885LMNA 1861/4885 |
| US-11919922-B2 | Bicyclic nucleosides and oligomers prepared therefrom | RRM2, REV1, NUDT1 | POLA1 69/4885PNP 9/4885LMNA 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.