Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955288 | 0.82 | TLR7 (0.42) | CDK1CCNB1CCNE1CDK2PI4KA | |
| SCHEMBL2952316 | 0.79 | NPC1 (0.51) | BCHEMAOAACHEMAOBSRC | |
| SCHEMBL2951937 | 0.78 | DHFR (0.45) | CDK1CCNB1CCNE1CDK2PI4KA | |
| SCHEMBL2955191 | 0.73 | LMNA (0.45) | TLR8MMP13EGFRCSF1RMAPK14 | |
| SCHEMBL3707475 | 0.71 | LMNA (0.49) | MMP13EGFRCSF1R | |
| SCHEMBL2953607 | 0.71 | TLR7 (0.44) | CDK1CCNB1CCNE1CDK2PTPN1 | |
| SCHEMBL2950165 | 0.71 | TLR7 (0.41) | CDK1CCNB1CCNE1CDK2PI4KA | |
| SCHEMBL2952950 | 0.70 | DHFR (0.43) | — | |
| SCHEMBL2953257 | 0.69 | CDK1 (0.42) | TLR8CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL2946049 | 0.69 | DHFR (0.42) | CDK1CCNB1CCNE1CDK2CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |