Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034338 | 0.88 | TSHR (0.37) | MAPK1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3033304 | 0.85 | ALDH1A1 (0.45) | KMT2AHTTSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL3031209 | 0.83 | GAA (0.40) | CYP2C19KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL3412865 | 0.74 | LMNA (0.34) | KMT2AMAPK1HTTSMN1; SMN2MAPT | |
| SCHEMBL5069635 | 0.74 | LMNA (0.34) | KMT2AMAPK1HTTSMN1; SMN2MAPT | |
| SCHEMBL3030864 | 0.72 | PIM1 (0.36) | ALDH1A1 | |
| SCHEMBL3039262 | 0.72 | ALDH1A1 (0.37) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL1906001 | 0.70 | LMNA (0.36) | KMT2AHTTMAPTL3MBTL1KDM4E | |
| SCHEMBL17024319 | 0.67 | — | — | |
| SCHEMBL2944560 | 0.66 | ALDH1A1 (0.41) | CYP2C19HTTSMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |
| EP-2727909-A1 | Inhibitors of focal adhesion kinase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-05-07 | — | — | EP | disclosed |