Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946349 | 0.85 | CYP2C19 (0.36) | ALDH1A1MAPTSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL3034338 | 0.80 | TSHR (0.37) | ALDH1A1SMN1; SMN2TSHRKDM4ENPSR1 | |
| SCHEMBL2944560 | 0.78 | ALDH1A1 (0.41) | ALDH1A1POLBMAPTCA12CA7 | |
| SCHEMBL3031209 | 0.72 | GAA (0.40) | ALDH1A1SMN1; SMN2GAALMNAKMT2A | |
| SCHEMBL3039262 | 0.66 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17149209 | 0.64 | MAPT (0.73) | ALDH1A1POLBMAPTCA12CA7 | |
| SCHEMBL4724826 | 0.64 | CA12 (1.00) | ALDH1A1POLBMAPTCA12CA7 | |
| SCHEMBL3030864 | 0.63 | PIM1 (0.36) | ALDH1A1 | |
| SCHEMBL3412865 | 0.62 | LMNA (0.34) | ALDH1A1POLBMAPTSMN1; SMN2TSHR | |
| SCHEMBL5069635 | 0.62 | LMNA (0.34) | ALDH1A1POLBMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |