Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034338 | 0.83 | TSHR (0.37) | ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL2946349 | 0.83 | CYP2C19 (0.36) | LMNAALDH1A1CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL3033304 | 0.72 | ALDH1A1 (0.45) | GAALMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3030864 | 0.69 | PIM1 (0.36) | ALDH1A1 | |
| SCHEMBL3039262 | 0.67 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL13178108 | 0.65 | TTK (0.48) | GAATHRBLMNAHPGDSTTK | |
| SCHEMBL7562139 | 0.65 | CHRM5 (0.48) | GAATHRBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14535216 | 0.65 | CHRM5 (0.48) | GAATHRBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12321702 | 0.64 | NCF1 (0.45) | GAATHRBLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29367 | 0.64 | MAPT (0.46) | GAATHRBLMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |