Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498709 | 0.76 | — | — | |
| SCHEMBL13167977 | 0.75 | ACACB (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3268479 | 0.73 | SPR (0.31) | — | |
| SCHEMBL13167978 | 0.73 | ACACB (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1344157 | 0.73 | ACACB (0.39) | BACE1 | |
| SCHEMBL728681 | 0.72 | ACACB (0.41) | — | |
| SCHEMBL2886584 | 0.72 | ACACB (0.33) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL3267352 | 0.72 | ACACB (0.33) | — | |
| SCHEMBL2951808 | 0.72 | PKM (0.31) | — | |
| SCHEMBL3273870 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314254-B2 | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2012-11-20 | — | — | US | disclosed |
| US-20100234229-A1 | Substituted Spirocyclic Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-09-16 | — | — | US | disclosed |
| US-7754654-B2 | Substituted spirocyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2010-07-13 | — | — | US | disclosed |
| US-20070275858-A1 | SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275858-A1 | SUBSTITUTED SPIROCYCLIC KETOENOLS | PDHX, CYP19A1, AKR1A1 | CHRM2 648/4885CHRM4 981/4885CHRM5 1009/4885 |
| US-20100234229-A1 | Substituted Spirocyclic Ketoenols | HSD17B7, CYP17A1, HSD17B11 | CHRM2 3196/4885CHRM4 3372/4885CHRM5 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.