Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 4/20 | 0.37 |
| ▸ | SRC | P12931 | 4/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953453 | 0.84 | CRHR1 (0.40) | CRHR1CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL2953257 | 0.83 | CDK1 (0.42) | CRHR1CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL2952316 | 0.77 | NPC1 (0.51) | SRCMAOB | |
| SCHEMBL2946524 | 0.75 | HRH4 (0.43) | CDK1CCNB1CDK2DCPSCHEK1 | |
| SCHEMBL3701226 | 0.74 | GAA (0.49) | — | |
| SCHEMBL2950165 | 0.71 | TLR7 (0.41) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL2955288 | 0.70 | TLR7 (0.42) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL2950527 | 0.69 | ADORA2A (0.42) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL2951209 | 0.69 | KDM4E (0.42) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL2951937 | 0.68 | DHFR (0.45) | CDK1CCNB1CCNE1CDK2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |