SCHEMBL2948052

SCHEMBL2948052

CCNC(=O)c1noc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 15/20 1.00
HSP90AA1 P07900 13/20 1.00
HDAC3 O15379 5/20 0.77
HDAC4 P56524 5/20 0.77
HDAC1 Q13547 5/20 0.77
HDAC7 Q8WUI4 5/20 0.77
HDAC2 Q92769 5/20 0.77
HDAC10 Q969S8 5/20 0.77
HDAC11 Q96DB2 5/20 0.77
HDAC8 Q9BY41 5/20 0.77
HDAC6 Q9UBN7 5/20 0.77
HDAC9 Q9UKV0 5/20 0.77
HDAC5 Q9UQL6 5/20 0.77
PDK1 Q15118 4/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370045 1.00 HSP90AB1 (1.00) HSP90AB1HSP90AA1HDAC3HDAC4HDAC1
SCHEMBL5322935 0.90 HSP90AB1 (0.81) HSP90AB1HSP90AA1HDAC3HDAC4HDAC1
SCHEMBL19602919 0.89 HSP90AB1 (0.80) HSP90AB1HSP90AA1HDAC3HDAC4HDAC1
SCHEMBL23384354 0.89 HSP90AB1 (0.80) HSP90AB1HSP90AA1HDAC3HDAC4HDAC1
SCHEMBL12939036 0.88 HSP90AA1 (0.78) HSP90AB1HSP90AA1HDAC3HDAC4HDAC1
SCHEMBL5323916 0.88 HSP90AA1 (0.78) HSP90AB1HSP90AA1HDAC3HDAC4HDAC1
SCHEMBL5323922 0.88 HDAC3 (0.81) HSP90AB1HSP90AA1HDAC3HDAC4HDAC1
SCHEMBL3957402 0.87 HDAC3 (0.78) HSP90AB1HSP90AA1HDAC3HDAC4HDAC1
SCHEMBL3959474 0.87 HDAC3 (0.78) HSP90AB1HSP90AA1HDAC3HDAC4HDAC1
SCHEMBL4255576 0.87 HDAC3 (1.00) HSP90AB1HSP90AA1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4637832-A1 CONJUGATES COMPRISING A PHOSPHORUS(V) MOIETY AND A DRUG Tubulis GmbH (DE) 2025-10-29 EP claimed
CN-120136941-A Anti-aging composition and application thereof 鲁贝多生命科学公司 2025-06-13 CN claimed
US-20240269313-A1 CONJUGATES COMPRISING A PHOSPHORUS(V) MOIETY AND A DRUG TUBULIS GMBH (DE) 2024-08-15 US claimed
WO-2024133845-A1 CONJUGATES COMPRISING A PHOSPHORUS(V) MOIETY AND A DRUG TUBULIS GMBH (DE) 2024-06-27 WO claimed
US-20230321130-A1 Senolytic Compositions and Uses Thereof Rubedo Life Sciences, Inc. 2023-10-12 US claimed
CN-115381816-A Application of VER50589 in preparing medicine for resisting enterovirus 71 武汉市金银潭医院(武汉市传染病医院) 2022-11-25 CN claimed
US-20220362276-A1 Small Molecule Inhibitors of Viral Replication THE TRUSTEES OF PRINCETON UNIVERSITY 2022-11-17 US claimed
US-20220273664-A1 Mitochondrial Targeted Releasable Linker THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2022-09-01 US claimed
EP-4642465-A1 A CANCER ASSOCIATED FIBROBLAST (CAF) INHIBITOR FOR USE WITH AN ALTERNATING ELECTRIC FIELD IN A METHOD OF TREATING DISEASES SUCH AS CANCER Novocure GmbH (CH) 2025-11-05 EP disclosed
EP-4637832-A1 CONJUGATES COMPRISING A PHOSPHORUS(V) MOIETY AND A DRUG Tubulis GmbH (DE) 2025-10-29 EP disclosed
EP-4630004-A1 TREATMENT OF PROSTATE CANCER HAVING ANDROGEN RECEPTOR VARIANTS Oric Pharmaceuticals, Inc. (US) 2025-10-15 EP disclosed
US-20250305055-A1 PROGNOSTIC/PREDICTIVE BREAST CANCER SIGNATURE CORNELL UNIVERSITY 2025-10-02 US disclosed
US-12427192-B2 Water soluble adjuvant and composition containing same Sumitomo Pharma Co., Ltd. (JP) 2025-09-30 US disclosed
EP-4615869-A1 COMBINATION THERAPY COMPRISING BISPECIFIC ANTIBODIES COMPRISING AN NRP1 BINDING DOMAIN Pinetree Therapeutics, Inc. (US) 2025-09-17 EP disclosed
US-20100093824-A1 METHODS OF TREATING VIRAL INFECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2010-04-15 US disclosed
WO-2008143647-A2 METHODS OF TREATING VIRAL INFECTION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2008-11-27 WO disclosed
WO-2007096194-A1 RADIO-LABELED ISOXAZOLE DERIVATIVES USEFUL FOR THE LABELING AND DIAGNOSTIC OF HSP90 FUNCTIONALITY NOVARTIS AG (CH) 2007-08-30 WO disclosed
US-20060241106-A1 Isoxazole compounds as inhibitors of heat shock proteins VERNALIS DEVELOPMENT LIMITED (GB) 2006-10-26 US disclosed
EP-1611112-A1 ISOXAZOLE COMPOUNDS AS INHIBITORS OF HEAT SHOCK PROTEINS Vernalis (Cambridge) Limited (GB) 2006-01-04 EP disclosed
WO-2004072051-A1 ISOXAZOLE COMPOUNDS AS INHIBITORS OF HEAT SHOCK PROTEINS VERNALIS (CAMBRIDGE) LIMITED (GB) 2004-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093824-A1 METHODS OF TREATING VIRAL INFECTION EIF2AK2, NSUN2, NSUN3 HSP90AB1 250/4885HSP90AA1 375/4885HDAC3 632/4885
US-20220362276-A1 Small Molecule Inhibitors of Viral Replication HSPH1, HSP90AB1, HSP90AA1 HSP90AB1 2/4885HSP90AA1 3/4885HDAC3 2717/4885
US-20220273664-A1 Mitochondrial Targeted Releasable Linker PDF, NDUFAB1, AURKAIP1 HSP90AB1 866/4885HSP90AA1 1161/4885HDAC3 1942/4885
US-20060241106-A1 Isoxazole compounds as inhibitors of heat shock proteins HSP90AB1, HSP90AA1, HSP90AB2P HSP90AB1 1/4885HSP90AA1 2/4885HDAC3 1029/4885
US-12427192-B2 Water soluble adjuvant and composition containing same TP53, MYD88, AQP1 HSP90AB1 296/4885HSP90AA1 240/4885HDAC3 4651/4885
US-20230321130-A1 Senolytic Compositions and Uses Thereof SENP3, SENP6, SENP1 HSP90AB1 620/4885HSP90AA1 517/4885HDAC3 273/4885
US-20240269313-A1 CONJUGATES COMPRISING A PHOSPHORUS(V) MOIETY AND A DRUG PTH1R, SELPLG, CALCR HSP90AB1 3057/4885HSP90AA1 3832/4885HDAC3 3467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.