SCHEMBL29509771

SCHEMBL29509771

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)CO)[C@@H](C)CC)C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)CC)[C@@H](C)CC

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 6/20 0.50
▸ CALCR P30988 4/20 0.49
▸ NTSR1 P30989 3/20 0.48
▸ NPY1R P25929 1/20 0.46
▸ NPY2R P49146 1/20 0.46
▸ NPY4R P50391 1/20 0.46
▸ NPY5R Q15761 1/20 0.46
▸ AGTR1 P30556 1/20 0.46
▸ NTSR2 O95665 1/20 0.46
▸ SORT1 Q99523 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29826838 0.93 OPRD1 (0.59) OPRD1CALCRNTSR1
SCHEMBL29509550 0.93 OPRD1 (0.59) OPRD1CALCRNTSR1
SCHEMBL31462127 0.87 EP300 (0.48) CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL31462047 0.87 CALCR (0.49) CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL31462080 0.87 CALCR (0.48) CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL31336659 0.86 NTSR1 (0.50) OPRD1NTSR1NPY1RNPY2RNPY4R
SCHEMBL31174232 0.86 NTSR1 (0.51) OPRD1CALCRNTSR1NTSR2SORT1
SCHEMBL31461927 0.85 CALCRL (0.46) OPRD1CALCRNTSR1
SCHEMBL30457013 0.85 OPRD1 (0.63) OPRD1NTSR1NTSR2SORT1
SCHEMBL30497011 0.85 OPRD1 (0.67) OPRD1CALCRNTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3864028-B1 OLIGONUCLEOTIDE-BASED TUNING OF PORE-FORMING PEPTIDES FOR INCREASING PORE SIZE, MEMBRANE AFFINITY, STABILITY, AND ANTIMICROBIAL ACTIVITY ADOLPHE MERKLE INSTITUTE UNIV OF FRIBOURG (CH) 2026-03-25 — — EP claimed
US-12281178-B2 Tuning of pore-forming peptides for increasing pore size, membrane affinity, stability, and antimicrobial activity ADOLPHE MERKLE INSTITUTE, UNIVERSITY OF FRIBOURG (CH) 2025-04-22 — — US claimed
CN-113166209-B Oligonucleotide-based modulation of pore-forming peptides to increase pore size, membrane affinity, stability and antimicrobial activity 弗里堡大学阿道夫梅克尔研究所 2025-01-07 — — CN claimed
EP-3864028-B1 OLIGONUCLEOTIDE-BASED TUNING OF PORE-FORMING PEPTIDES FOR INCREASING PORE SIZE, MEMBRANE AFFINITY, STABILITY, AND ANTIMICROBIAL ACTIVITY ADOLPHE MERKLE INSTITUTE UNIV OF FRIBOURG (CH) 2026-03-25 — — EP disclosed
EP-3574909-B1 POLYELECTROLYTE MULTILAYER COMPRISING SILVER FOR WOUND HEALING IMBED BIOSCIENCES INC (US) 2026-03-04 — — EP disclosed
US-12564617-B2 Methods for modulating macrophage activity Riptide Bioscience, Inc. (US) 2026-03-03 — — US disclosed
US-20260000805-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING IMBED BIOSCIENCES INC (US) 2026-01-01 — — US disclosed
US-12409247-B2 Methods and compositions for wound healing IMBED BIOSCIENCES INC. (US) 2025-09-09 — — US disclosed
US-12359240-B2 Membrane protease-based methods for detection of bacteria NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2025-07-15 — — US disclosed
US-12281178-B2 Tuning of pore-forming peptides for increasing pore size, membrane affinity, stability, and antimicrobial activity ADOLPHE MERKLE INSTITUTE, UNIVERSITY OF FRIBOURG (CH) 2025-04-22 — — US disclosed
CN-113166209-B Oligonucleotide-based modulation of pore-forming peptides to increase pore size, membrane affinity, stability and antimicrobial activity 弗里堡大学阿道夫梅克尔研究所 2025-01-07 — — CN disclosed
US-20240009342-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING IMBED BIOSCIENCES INC. 2024-01-11 — — US disclosed
EP-4289910-A2 METHODS AND COMPOSITIONS FOR WOUND HEALING Imbed Biosciences, Inc. (US) 2023-12-13 — — EP disclosed
EP-3490622-B1 METHODS AND COMPOSITIONS FOR WOUND HEALING IMBED BIOSCIENCES INC (US) 2023-09-06 — — EP disclosed
WO-2023141679-A1 DIMERS AND USES THEREFOR THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH (AU) 2023-08-03 — — WO disclosed
US-11554194-B2 Methods and compositions for wound healing IMBED BIOSCIENCES INC. (US) 2023-01-17 — — US disclosed
US-20220205015-A1 MEMBRANE PROTEASE-BASED METHODS FOR DETECTION OF BACTERIA NORTHWESTERN UNIVERSITY 2022-06-30 — — US disclosed
EP-3995158-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING Imbed Biosciences, Inc. (US) 2022-05-11 — — EP disclosed
US-20220062373-A1 Methods for Modulating Macrophage Activity Riptide Bioscience, Inc. 2022-03-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564617-B2 Methods for modulating macrophage activity MSR1, CSF1R, CD209 OPRD1 585/4885CALCR 355/4885NTSR1 237/4885
US-20260000805-A1 METHODS AND COMPOSITIONS FOR WOUND HEALING PCNA, ARG1, PLOD3 OPRD1 2565/4885CALCR 2540/4885NTSR1 3816/4885
US-20220062373-A1 Methods for Modulating Macrophage Activity CD209, CD68, CD14 OPRD1 1827/4885CALCR 272/4885NTSR1 275/4885
US-20220205015-A1 MEMBRANE PROTEASE-BASED METHODS FOR DETECTION OF BACTERIA PDXK, PPOX, PCNP OPRD1 1711/4885CALCR 3664/4885NTSR1 1738/4885
US-12359240-B2 Membrane protease-based methods for detection of bacteria PDXK, PPOX, PCNP OPRD1 1711/4885CALCR 3664/4885NTSR1 1738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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