SCHEMBL29521629

SCHEMBL29521629

C[C@H](CC[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(C)(C)O)[C@H]1CC[C@@]2(C)[C@@H]3CC=C4[C@@H](CC[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)C4(C)C)[C@]3(C)C(=O)C[C@]12C

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PRKAG1 P54619 3/20 0.40
▸ PRKAA2 P54646 3/20 0.40
▸ PRKAB1 Q9Y478 3/20 0.40
▸ F3 P13726 3/20 0.38
▸ PTPN1 P18031 3/20 0.38
▸ TYR P14679 1/20 0.38
▸ PAX8 Q06710 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ TOP1 P11387 3/20 0.35
▸ POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18805297 1.00 PRKAG1 (0.40) PRKAG1PRKAA2PRKAB1F3PTPN1
SCHEMBL24503392 1.00 PRKAG1 (0.40) PRKAG1PRKAA2PRKAB1F3PTPN1
SCHEMBL18805188 0.98 PRKAG1 (0.38) PRKAG1PRKAA2PRKAB1F3PTPN1
SCHEMBL23685930 0.97 PRKAG1 (0.38) PRKAG1PRKAA2PRKAB1F3PTPN1
SCHEMBL24859162 0.97 PRKAG1 (0.39) PRKAG1PRKAA2PRKAB1F3PTPN1
SCHEMBL21980463 0.97 PRKAG1 (0.39) PRKAG1PRKAA2PRKAB1F3PTPN1
SCHEMBL23686027 0.97 PRKAG1 (0.39) PRKAG1PRKAA2PRKAB1F3PTPN1
SCHEMBL23028864 0.97 PRKAG1 (0.39) PRKAG1PRKAA2PRKAB1F3PTPN1
SCHEMBL23685906 0.97 PRKAG1 (0.39) PRKAG1PRKAA2PRKAB1F3PTPN1
SCHEMBL23633959 0.97 PRKAG1 (0.39) PRKAG1PRKAA2PRKAB1F3PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 — — US claimed
CN-117750886-A Salt-containing beverage with improved taste 可口可乐公司 2024-03-22 — — CN claimed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 — — US claimed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 — — US claimed
US-20260130404-A1 SWEETNESS AND TASTE IMPROVEMENT OF NON-SUCROSE SWEETENERS WITH D-SUGARS OR L-SUGARS THE COCA COLA CO (US) 2026-05-14 — — US disclosed
US-12557831-B2 Mogrosides and uses of the same THE COCA-COLA COMPANY (US) 2026-02-24 — — US disclosed
US-12495818-B2 Dihydrochalcones from Balanophora harlandii THE COCA-COLA COMPANY (US) 2025-12-16 — — US disclosed
US-12428662-B2 Methods for making high intensity sweeteners FIRMENICH INCORPORATED (US) 2025-09-30 — — US disclosed
EP-4608168-A1 SWEETNESS AND TASTE IMPROVEMENT OF NON-SUCROSE SWEETENERS WITH D-SUGARS OR L-SUGARS The Coca-Cola Company (US) 2025-09-03 — — EP disclosed
EP-3614860-B1 SWEETNESS AND TASTE IMPROVEMENT OF STEVIOL GLYCOSIDE AND MOGROSIDE SWEETENERS WITH DIHYDROCHALCONES COCA COLA CO (US) 2025-07-02 — — EP disclosed
US-12338476-B2 Methods for making high intensity sweeteners FIRMENICH INCORPORATED (US) 2025-06-24 — — US disclosed
US-12286661-B2 Methods for making high intensity sweeteners FIRMENICH INCORPORATED (US) 2025-04-29 — — US disclosed
CN-115666265-A Beverage with enhanced flavor comprising siamenoside I 可口可乐公司 2023-01-31 — — CN disclosed
CN-115484828-A Fat-free non-dairy cream composition 可口可乐公司 2022-12-16 — — CN disclosed
US-20220287346-A1 STABLE CREATINE BEVERAGES THE COCA-COLA COMPANY 2022-09-15 — — US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 — — EP disclosed
CN-114630587-A Stabilized creatine beverage 可口可乐公司 2022-06-14 — — CN disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 — — US disclosed
US-20220142216-A1 Novel Mogrosides and Uses of the Same THE COCA-COLA COMPANY 2022-05-12 — — US disclosed
WO-2022056224-A1 WATER-SOLUBLE FILM FOR PREPARING A BEVERAGE THE COCA-COLA COMPANY (US) 2022-03-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 PRKAG1 1642/4885PRKAA2 1849/4885PRKAB1 1634/4885
US-12428662-B2 Methods for making high intensity sweeteners OXER1, MAN1B1, GMDS PRKAG1 1166/4885PRKAA2 2993/4885PRKAB1 1642/4885
US-20260130404-A1 SWEETNESS AND TASTE IMPROVEMENT OF NON-SUCROSE SWEETENERS WITH D-SUGARS OR L-SUGARS TAS2R40, TAS2R13, TAS2R31 PRKAG1 1856/4885PRKAA2 3570/4885PRKAB1 1963/4885
US-12557831-B2 Mogrosides and uses of the same TAS2R40, TAS2R20, TAS2R10 PRKAG1 897/4885PRKAA2 3319/4885PRKAB1 1891/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 PRKAG1 1642/4885PRKAA2 1849/4885PRKAB1 1634/4885
US-12495818-B2 Dihydrochalcones from Balanophora harlandii TAS2R46, TAS2R20, TAS2R50 PRKAG1 3281/4885PRKAA2 1638/4885PRKAB1 3083/4885
US-20220142216-A1 Novel Mogrosides and Uses of the Same MAG, UGGT1, OGT PRKAG1 2543/4885PRKAA2 4734/4885PRKAB1 3684/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 PRKAG1 1642/4885PRKAA2 1849/4885PRKAB1 1634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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