Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | TTK | P33981 | 3/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.39 |
| ▸ | INSR | P06213 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953119 | 0.95 | TTK (0.43) | SMPD3TTKCAMK2DALKINSR | |
| SCHEMBL2952077 | 0.91 | INSR (0.42) | ALKINSRIGF1RFGFR1FGFR4 | |
| SCHEMBL2952950 | 0.87 | DHFR (0.43) | TTKALKINSR | |
| SCHEMBL2954051 | 0.80 | DHFR (0.44) | — | |
| SCHEMBL2946049 | 0.79 | DHFR (0.42) | TTK | |
| SCHEMBL30399128 | 0.79 | FYN (0.41) | — | |
| SCHEMBL2948890 | 0.78 | TTK (0.45) | TTKALKINSRIGF1R | |
| SCHEMBL2952277 | 0.77 | MAP4K4 (0.45) | SMPD3MAP4K4HRH3PIK3CD | |
| SCHEMBL520455 | 0.75 | SMPD3 (0.44) | SMPD3MAP4K4TTKCAMK2DALK | |
| SCHEMBL2951937 | 0.75 | DHFR (0.45) | KDRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |