SCHEMBL29545883

SCHEMBL29545883

CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)O)[C@@H](C)O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CRHR1 P34998 1/20 0.58
▸ CRHR2 Q13324 1/20 0.58
▸ CALCR P30988 4/20 0.57
▸ BACE1 P56817 3/20 0.56
▸ GLP1R P43220 4/20 0.54
▸ VIPR1 P32241 3/20 0.54
▸ VIPR2 P41587 5/20 0.53
▸ KEAP1 Q14145 1/20 0.53
▸ BACE2 Q9Y5Z0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30432084 0.89 BACE1 (0.61) CRHR1CRHR2CALCRBACE1GLP1R
SCHEMBL30607339 0.89 CRHR1 (0.63) CRHR1CRHR2CALCRGLP1RVIPR1
SCHEMBL30680637 0.87 BACE1 (0.58) BACE1GLP1RVIPR1BACE2
SCHEMBL31307253 0.87 CRHR1 (0.49) CRHR1CRHR2CALCRBACE1GLP1R
SCHEMBL29463758 0.87 CALCR (0.57) CRHR1CRHR2CALCRBACE1GLP1R
SCHEMBL30262081 0.87 CALCR (0.59) CRHR1CRHR2CALCRGLP1RKEAP1
Aviptadil SCHEMBL30969141 0.86 VIPR1 (0.72) CRHR1CRHR2CALCRGLP1RVIPR1
Vasoactive Intestinal Peptide SCHEMBL3041046 0.86 VIPR1 (0.72) CRHR1CRHR2CALCRGLP1RVIPR1
SCHEMBL31182789 0.86 GLP1R (0.60) GLP1RVIPR1VIPR2KEAP1
SCHEMBL29496487 0.86 F2 (0.53) CALCRBACE1GLP1RBACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220153783-A1 MITOCHONDRIA-TARGETING COMPOUND AND COMPOSITION COMPRISING SAME FOR TREATING OR PREVENTING AGING-RELATED DISEASES FUSION BIOTECHNOLOGY CO., LTD. (KR) 2022-05-19 — — US claimed
US-20260097092-A1 PHARMACEUTICAL COMPOSITION CONTAINING MITOCHONDRIA-TARGETING COMPOUND AS ACTIVE INGREDIENT FOR TREATING MACULAR DEGENERATION ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-04-09 — — US disclosed
WO-2024063223-A1 PHARMACEUTICAL COMPOSITION CONTAINING MITOCHONDRIA-TARGETING COMPOUND AS ACTIVE INGREDIENT FOR TREATING MACULAR DEGENERATION 울산과학기술원 2024-03-28 — — WO disclosed
US-20220153783-A1 MITOCHONDRIA-TARGETING COMPOUND AND COMPOSITION COMPRISING SAME FOR TREATING OR PREVENTING AGING-RELATED DISEASES FUSION BIOTECHNOLOGY CO., LTD. (KR) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097092-A1 PHARMACEUTICAL COMPOSITION CONTAINING MITOCHONDRIA-TARGETING COMPOUND AS ACTIVE INGREDIENT FOR TREATING MACULAR DEGENERATION ARG2, NLN, RHOT2 CRHR1 3979/4885CRHR2 3875/4885CALCR 2789/4885
US-20220153783-A1 MITOCHONDRIA-TARGETING COMPOUND AND COMPOSITION COMPRISING SAME FOR TREATING OR PREVENTING AGING-RELATED DISEASES TFAM, HSPA9, AIFM1 CRHR1 4581/4885CRHR2 4509/4885CALCR 4358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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