Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.59 |
| ▸ | AGXT | P21549 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.45 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.45 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557935 | 1.00 | ADRA2C (0.59) | ADRA2CAGXTHTR3APLOD2PLOD3 | |
| SCHEMBL12266120 | 0.86 | MGLL (0.50) | HTR3AKDM4EALDH1A1ENPP2DRD3 | |
| SCHEMBL19492816 | 0.84 | ENPP2 (0.48) | ADRA2CAGXTKDM4EALDH1A1ENPP2 | |
| SCHEMBL488570 | 0.84 | KDM4E (0.51) | AGXTKDM4EALDH1A1ENPP2HTR6 | |
| SCHEMBL1529259 | 0.82 | ALDH1A1 (0.50) | AGXTKDM4EALDH1A1ENPP2GAA | |
| Hydrochloric Acid SCHEMBL2379090 | 0.82 | KDM4E (0.50) | AGXTKDM4EALDH1A1ENPP2HTR6 | |
| Hydrochloric Acid SCHEMBL29957597 | 0.82 | KDM4E (0.50) | AGXTKDM4EALDH1A1ENPP2HTR6 | |
| SCHEMBL2552859 | 0.81 | GFER (0.50) | ALDH1A1HTR1AHTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL29955844 | 0.81 | ALDH1A1 (0.49) | AGXTKDM4EALDH1A1ENPP2GAA | |
| SCHEMBL31467151 | 0.80 | FAAH (0.49) | KDM4EALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306096-B2 | 4,6 dihydropyrrolo [3,4-C] pyrazole-5 (1H)-carbonitrile derivates for treating cancer | MISSION THERAPEUTICS LIMITED (GB) | 2022-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11306096-B2 | 4,6 dihydropyrrolo [3,4-C] pyrazole-5 (1H)-carbonitrile derivates for treating cancer | USP7, USP1, USP3 | ADRA2C 2556/4885AGXT 2969/4885HTR3A 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.